Protein Name: Tropomyosin alpha-3 chain
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UniprotKB/SwissProt ID: TPM3_HUMAN (P06753)
Gene Name: TPM3
Organism: Homo sapiens (Human).
Function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | HPRD | 01840 | Nemaline myopathy 1 |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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