Protein Name: TNF receptor-associated factor 5
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UniprotKB/SwissProt ID: TRAF5_HUMAN (O00463)
Gene Name: TRAF5
Synonyms: RNF84
Organism: Homo sapiens (Human).
Function: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (Probable). Cytoplasm, cytosol.
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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