UniprotKB/SwissProt ID: TWF2_HUMAN (Q6IBS0)
Gene Name: TWF2
Synonyms: PTK9L
Organism: Homo sapiens (Human).
Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium (By similarity). Note=Perinuclear and G-actin-rich cortical actin structure sublocalization.
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