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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ubiquitin-like modifier-activating enzyme 1

UniprotKB/SwissProt ID: UBA1_MOUSE (Q02053)

Gene Name: Uba1

Synonyms: Sbx, Ube1, Ube1ax, Ube1x

Organism: Mus musculus (Mouse).

Function: Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map05012Parkinson's disease
map04120Ubiquitin mediated proteolysis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1Z7L X-ray 2.80 A A/B/C626-891Link
2LZJ NMR - A202-312Link
2V31 NMR - A203-312Link

The S-nitrosylation sites of UBA1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1234VTKDNPGVVT C LDEARHGFET   2.81%MC0224926564-
2234VTKDNPGVVT C LDEARHGFET   2.81%MC0221278135in vitro
3340HIGFQALHQF C ALHNQPPRPR   2.95%MC1220837516in vivo