Protein Name: NEDD8-conjugating enzyme Ubc12
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UniprotKB/SwissProt ID: UBC12_MOUSE (P61082)
Gene Name: Ube2m
Synonyms: Ubc-rs2, Ubc12
Organism: Mus musculus (Mouse).
Function: Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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