logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: E3 UFM1-protein ligase 1

UniprotKB/SwissProt ID: UFL1_HUMAN (O94874)

Gene Name: UFL1

Synonyms: KIAA0776, NLBP

Organism: Homo sapiens (Human).

Function: E3 UFM1-protein ligase that mediates ufmylation of target proteins such as DDRGK1/C20orf116. The function of ufmylation is unknown. May act as a tumor suppressor by inhibiting cell invasion, blocking NF-kappa-B signaling and increasing stability of CDK5RAP3.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum. Cytoplasm. Note=In cytoplasm colocalizes with CDK5RAP3.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of UFL1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1708THSMLHAPGR C VPQIIAFLNS   6.93%HC0219483679in vivo