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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: V-type proton ATPase subunit B, brain isoform

UniprotKB/SwissProt ID: VATB2_MOUSE (P62814)

Gene Name: Atp6v1b2

Synonyms: Atp6b2, Vat2

Organism: Mus musculus (Mouse).

Function: Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endomembrane system; Peripheral membrane protein. Melanosome (By similarity). Note=Endomembrane.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00190Oxidative phosphorylation
map04721Synaptic vesicle cycle
map04966Collecting duct acid secretion
map05323Rheumatoid arthritis
map04145Phagosome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000194
IPR000793
IPR004100
IPR005723

The S-nitrosylation sites of VATB2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1112TSGIDAKKTS C EFTGDILRTP CCCCCCCCCE E EECCCEEEEE 6.37%MC1024895380
(Cys289)
-
2112TSGIDAKKTS C EFTGDILRTP CCCCCCCCCE E EECCCEEEEE 6.37%MC1024926564-
3207LPHNEIAAQI C RQAGLVKKSK CCHHHHHHHH H HHHHHHCCCC 1.43%MC0524926564-
4289LTTAEFLAYQ C EKHVLVILTD HHHHHHHHHH C CCEEEEEEEC 4.98%MC0622588120-
5289LTTAEFLAYQ C EKHVLVILTD HHHHHHHHHH C CCEEEEEEEC 4.98%MC0624895380
(Cys112)
-