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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: V-type proton ATPase subunit C 1

UniprotKB/SwissProt ID: VATC1_MOUSE (Q9Z1G3)

Gene Name: Atp6v1c1

Synonyms: Atp6c, Atp6c1, Vatc

Organism: Mus musculus (Mouse).

Function: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Network with metabolic pathway:
Kegg map ID Pathway Link
map00190Oxidative phosphorylation
map04721Synaptic vesicle cycle
map04966Collecting duct acid secretion
map05323Rheumatoid arthritis
map04145Phagosome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004907

The S-nitrosylation sites of VATC1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1376YYPYVYYKID C NLLEFK---- CCCEEEEEEE C EEECCC 4.38%MC0220925432in vivo