Protein Name: Voltage-dependent anion-selective channel protein 2
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UniprotKB/SwissProt ID: VDAC2_HUMAN (P45880)
Gene Name: VDAC2
Organism: Homo sapiens (Human).
Function: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 193245 | VOLTAGE-DEPENDENT ANION CHANNEL 2; VDAC2 |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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