logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Vimentin

UniprotKB/SwissProt ID: VIME_HUMAN (P08670)

Gene Name: VIM

Organism: Homo sapiens (Human).

Function: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map05169Epstein-Barr virus infection
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001664
IPR006821

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1GK4 X-ray 2.30 A A/B/C/D/E/F328-411Link
1GK6 X-ray 1.90 A A/B385-412Link
1GK7 X-ray 1.40 A A102-138Link
3G1E X-ray 1.83 A A/B102-138Link
3KLT X-ray 2.70 A A/B/C/D263-334Link
3S4R X-ray 2.45 A A/B99-189Link
3SSU X-ray 2.60 A A/B99-189Link
3SWK X-ray 1.70 A A/B153-238Link
3TRT X-ray 2.30 A A/B261-335Link
3UF1 X-ray 2.81 A A/B/C/D144-251Link
4MCY X-ray 2.30 A C66-78Link
4MCZ X-ray 2.41 A C59-71Link
4MD0 X-ray 2.19 A C59-71Link
4MD5 X-ray 1.65 A C66-78Link
4MDI X-ray 2.00 A C66-78Link
4MDJ X-ray 1.70 A C66-78Link

The S-nitrosylation sites of VIME_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1328EYRRQVQSLT C EVDALKGTNE HHHHHHHHHH H HHHHHHHHHH 6.10%HC0122178444-
2328EYRRQVQSLT C EVDALKGTNE HHHHHHHHHH H HHHHHHHHHH 6.10%HC0125040305in vivo
3328EYRRQVQSLT C EVDALKGTNE HHHHHHHHHH H HHHHHHHHHH 6.10%HC0119447776-
4328EYRRQVQSLT C EVDALKGTNE HHHHHHHHHH H HHHHHHHHHH 6.10%HC0119483679in vivo