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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Synaptobrevin homolog YKT6

UniprotKB/SwissProt ID: YKT6_MOUSE (Q9CQW1)

Gene Name: Ykt6

Organism: Mus musculus (Mouse).

Function: Vesicular soluble NSF attachment protein receptor (v- SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol (By similarity). Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side (By similarity). Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Probably cycles through vesicles between Golgi and endosomes

Network with metabolic pathway:
Kegg map ID Pathway Link
map04130SNARE interactions in vesicular transport
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001388
IPR010908
IPR011012

The S-nitrosylation sites of YKT6_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
166RASVKEQEYL C HVYVRSDSLA CEEEEECCEE E EEEEEECCEE 1.68%MC0421278135in vitro