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Training data set for structure-based identification

 

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All Serine
All Threonine
All Tyrosine
Kinase-specific of Serine
Kinase-specific of Threonine
Kinase-specific of Tyrosine

 


 

Kinase-specific phosphorylation data for sequence-based identification

 

Data Set

Substrate Amino Acid

for Windows

for Linux

Independent Test Set

Serine(S)/Threonine(T) Kinase

Independent Test Set

Tyrosine(Y) Kinase

Training Set

Serine(S)/Threonine(T) Kinase

Training Set

Tyrosine(Y) Kinase

 

#

Kinase Group

Kinase Name

Description

Training Set

Independent Test Set

for Windows

for Linux

for Windows

for Linux

1
AGC
PKB
Protein kinase B
2
AGC
ROCK
Rho Kinase
3
AGC
GEK
Genghis Khan
-
-
4
AGC
GRK
G-protein coupled Receptor Kinase
5
AGC
BARK
Beta Adrenergic Receptor Kinase
6
AGC
NDR
Nuclear Dbf2-related kinases
-
-
7
AGC
PKA
Protein kinase A
8
AGC
PDK1
Phosphoinositide-dependent protein kinase
9
AGC
PKC
Protein kinase C
10
AGC
PKC Alpha
Protein kinase C, alpha
11
AGC
PKC Delta
Protein kinase C, delta
12
AGC
PKC Eta
Protein kinase C, eta
13
AGC
PKC Iota
Protein kinase C, iota
14
AGC
PKG
Protein kinase G
15
AGC
PKN
Protein kinase N
16
AGC
RSK
Ribosomal S6 Kinase
17
AGC
p70
p70 subfamily of Ribosomal Specific Kinase
-
-
18
AGC
MSK
Mitogen- and Stress-activated protein Kinase
19
AGC
SGK
Serum and Glucocorticoid Resposive Kinase
20
Atypical
ChaK
Channel Kinase
-
-
21
Atypical
PDHK
Pyruvate Dehydrogenase Kinase
-
-
22
Atypical
ATM
Ataxia telangiectasia mutated
23
Atypical
DNAPK
DNA Protein Kinase
24
Atypical
FRAP
FKBP12-rapamycin-associated protein
-
-
25
Atypical
TAF1
-
-
-
26
CAMK
CAMK1
CAMK family 1
27
CAMK
CAMK2
CAMK family 2
28
CAMK
NuaK
Novel (Nua) Kinase family
-
-
29
CAMK
QIK
Qin Induced Kinase
-
-
30
CAMK
MELK
Maternal Embryonic Leucine zipper Kinase
-
-
31
CAMK
AMPK
AMP-activated protein kinase
32
CAMK
CHK1
Checkpoint Kinase 1
-
-
33
CAMK
CHK2
Checkpoint Kinase 2
-
-
34
CAMK
LKB
-
-
-
35
CAMK
MARK
Microtubule Affinity Regulating Kinase
36
CAMK
BRSK
BRain Specific Kinase
-
-
37
CAMK
DAPK
Death Associated Protein Kinase
-
-
38
CAMK
MAPKAPK
MAP Kinase Associated Protein Kinase
39
CAMK
MNK
MAPK iNtegrating or iNteracting Kinase
-
-
40
CAMK
MLCK
Myosin Light Chain Kinases
-
-
41
CAMK
PHK
Phosphorylase Kinase
-
-
42
CAMK
PIM
-
43
CAMK
PKD
Protein Kinase D
44
CK1
CK1
Cell Kinase 1
45
CK1
TTBK
Tau Tubulin Kinase
-
-
46
CK1
VRK
Vaccinia Related Kinase
-
-
47
CMGC
CDK
Cyclin Dependent Kinase
48
CMGC
CDK7
Cyclin Dependent Kinase subfamily 7
-
-
49
CMGC
CDC2
Cell Division Control 2
50
CMGC
CK2
Casein kinase II
51
CMGC
CLK
CDC-Like Kinase, involved in splicing
-
-
52
CMGC
HIPK
Homeodomain Interacting Protein Kinases
-
-
53
CMGC
DYRK
Dual-specificity Tyrosine Regulated Kinase
-
-
54
CMGC
GSK
Gycogen Synthase 3 Kinase
55
CMGC
MAPK
Mitogen Activated Protein Kinase
56
CMGC
JNK
JNK subfamily of MAPK
57
CMGC
p38
p38 subfamily of MAPK
58
CMGC
ERK
Extracellular signal-Regulated protein Kinase
59
CMGC
nmo
nemo
-
-
60
Other
Aur
Aurora Kinase
-
-
61
Other
AurB
Aurora Kinase B
-
-
62
Other
AurA
Aurora Kinase B
-
-
63
Other
CAMKK
Metazoan-specific family of CAMK (Calcium/Calmodulin Regulated Kinase) Kinase
-
-
64
Other
IKK
I kappa Kinase
65
Other
NEK
Numb-Associated Kinase
66
Other
PKR
Interferon-induced, double-stranded RNA-activated protein kinase
67
Other
PLK
Polo Like Kinases
-
-
68
Other
TTK
-
-
-
69
Other
ULK
Unc-51 Like Kinase
-
-
70
Other
WEE
Homologs of yeast Wee1; cell cycle kinase
-
-
71
Other
WNK
With No Lysine kinases. Missing the canonical catalytic lysine, instead using a nearby lysine for catalysis
-
-
72
STE
MAP3K
MAP3K (MAP kinase kinase kinase) genes, homologous to yeast Ste 11
73
STE
PAK
p21-Activated protein Kinase
74
STE
PAKB
Class B p21-Activated protein Kinase
75
STE
PAKA
Class A p21-Activated protein Kinase
76
STE
YSK
Yeast SPS1/STE20-like kinase
-
-
77
STE
KHS
Kinase Homologous to STE20
-
-
78
STE
MSN
misshapen
-
-
79
STE
MST
Mammalian STE20-like kinase
-
-
80
STE
MAP2K
MAP2K (MAP kinase kinase) genes, homologous to yeast Ste 7
81
TK
Abl
Abelson murine leukemia homolog
82
TK
Ack
Activated Cdc42-associated tyrosine kinase
-
-
83
TK
Axl
-
-
-
84
TK
Csk
C-SRC kinase
85
TK
DDR
Discoidin Domain Receptor kinase
-
-
86
TK
EGFR
Epidermal Growth Factor Receptor
87
TK
Eph
Ephrin receptors
88
TK
FAK
Focal Adhesion Kinase
-
-
89
TK
Fer
Proto-oncogene tyrosine-protein kinase FER
-
-
90
TK
Fes
Proto-oncogene tyrosine-protein kinase Fes/Fps
-
-
91
TK
FGFR
Fibroblast Growth Factor Receptor
-
-
92
TK
InsR
Insulin Receptor and associated Kinases
93
TK
IGF1R
Insulin-like growth factor I receptor
-
-
94
TK
JakA
First (active) kinase domain of the dual-domain Janus Kinases
95
TK
TYK2
Non-receptor tyrosine-protein kinase
-
-
96
TK
Met
Met proto-oncogene tyrosine kinase
-
-
97
TK
PDGFR
Platelet-derived growth factor
-
-
98
TK
Fms
Platelet-derived growth factor, FMS
-
-
99
TK
Kit
Platelet-derived growth factor
-
-
100
TK
Ret
Proto-oncogene tyrosine-protein kinase receptor ret
101
TK
Brk
Proto-oncogene tyrosine-protein kinase BRK
-
-
102
TK
Fgr
Proto-oncogene tyrosine-protein kinase FGR
-
-
103
TK
Fyn
Proto-oncogene tyrosine-protein kinase FYN
104
TK
HCK
Proto-oncogene tyrosine-protein kinase HCK
105
TK
Lck
Proto-oncogene tyrosine-protein kinase Lck
106
TK
LYN
Tyrosine-protein kinase LYN
107
TK
Src
Proto-oncogene tyrosine-protein kinase Src
108
TK
YES
Proto-oncogene tyrosine-protein kinase YES
-
-
109
TK
SYK
Spleen tyrosine kinase
110
TK
ZAP70
70 kDa zeta-associated protein, Syk-related tyrosine kinase
111
TK
Tec
Tec protein tyrosine kinase family
112
TK
BTK
Bruton tyrosine kinase
-
-
113
TK
ITK
IL2-inducible T-cell kinase
-
-
114
TK
TXK
Tyrosine-protein kinase TXK
-
-
115
TK
Tie
Tunica interna endothelial cell kinase
-
-
116
TK
Trk
Neurotrophin receptor tyrosine kinases
117
TK
VEGFR
Vascular Endothelial Growth Factor Receptors
-
-
118
TKL
IRAK
IL1 Receptor Associated Kinase
-
-
119
TKL
RAF
RAF proto-oncogene serine/threonine-protein kinase
120
TKL
STKR Type1
Serine/Threonine Kinase Receptors; receptors for activin and TGFb ligands. Type 1
121
TKL
STKR Type2
Serine/Threonine Kinase Receptors; receptors for activin and TGFb ligands. Type 2
-
-
122
TKL
TGFbR
Serine/Threonine Kinase Receptors; receptors for TGFb ligands