Browse all E3 ligases (499 E3 ligases, wherein: HECT-type: 28; RING-type: 237; Other-type: 234)
| No. | ID | AC | Gene Name |
Group type |
Pubmed Reference | No. of |
Recognized motif | E3-Substrate Networks |
| 1 | HECD1_HUMAN | Q9ULT8 | HECTD1 | HECT | 20175895 | 4 |  | Construct |
| 2 | NED4L_HUMAN | Q96PU5 | NEDD4L | HECT | 19953087; 18577513; 18792916; 19617352; 18805448; 19473961; 19364400; 15576372; 20843805; 20504882; 21212261; 19615332; 17609522; 17322297; 21463633 | 17 |  | Construct |
| 3 | NEDD4_HUMAN | P46934 | NEDD4 | HECT | 19808888; 20086093; 19953087; 15013426; 19193720; 18286479; 12907674; 19125695; 17592138; 17137798; 15060076; 19864419; 20855896; 17996703; 21338354; 21320486; 21212261; 20159449; 18772139; 19787053; 19797085; 19054764; 11598133; 15703212; 15082780; 20559325; 15581898 | 43 |  | Construct |
| 4 | HERC5_HUMAN | Q9UII4 | HERC5 | HECT | 15331633; 20175895; 18535780 | 60 |  | Construct |
| 5 | HERC1_HUMAN | Q15751 | HERC1 | HECT | 20175895 | 4 |  | Construct |
| 6 | ITCH_HUMAN | Q96J02 | ITCH | HECT | 20650893; 18310276; 15013426; 19592251; 19580544; 19478092; 19433584; 19352540; 16387660; 19340001; 20300110; 19339247; 18278048; 17110928; 16087662; 16055720; 15946939; 20068034; 20818436; 18334649; 18922894; 15703212; 15082780; 21383157; 21212414; 21107885 | 47 |  | Construct |
| 7 | WWP2_HUMAN | O00308 | WWP2 | HECT | 20522958; 19651900; 15047715; 12202215 | 39 |  | Construct |
| 8 | HECW2_HUMAN | Q9P2P5 | HECW2 | HECT | 12890487; 18418053 | 2 |  | Construct |
| 9 | HUWE1_HUMAN | Q7Z6Z7 | HUWE1 | HECT | 18617514; 20007713; 18923429; 18923429; 18488021; 20210701; 16213503; 20624960 | 19 |  | Construct |
| 10 | TRIPC_HUMAN | Q14669 | TRIP12 | HECT | 20829358; 20175895; 20208519 18627766 | 21 |  | Construct |
| 11 | HECD3_HUMAN | Q5T447 | HECTD3 | HECT | 18194665; 20175895 | 1 |  | Construct |
| 12 | HECW1_HUMAN | Q76N89 | HECW1 | HECT | 19805045; 14684739 | 8 |  | Construct |
| 13 | G2E3_HUMAN | Q7L622 | G2E3 | HECT | 18511420; 20175895 | 8 |  | Construct |
| 14 | HERC3_HUMAN | Q15034 | HERC3 | HECT | 11163799 | 6 |  | Construct |
| 15 | HERC2_HUMAN | O95714 | HERC2 | HECT | 21193487; 20304803; 20631078 | 4 |  | Construct |
| 16 | HERC4_HUMAN | Q5GLZ8 | HERC4 | HECT | 20133869 | 1 |  | Construct |
| 17 | SMUF2_HUMAN | Q9HAU4 | SMURF2 | HECT | 16950122; 18927080; 19583833; 19255252; 20819168; 14562029; 20073064; 11389444; 11163210; 18671942; 14755250; 20858899 | 60 |  | Construct |
| 18 | SMUF1_HUMAN | Q9HCE7 | SMURF1 | HECT | 20512916; 19561075; 16472676; 14657501; 20621832; 18208356; 15820682; 20558834; 19937093; 21454619; 21382345 | 46 |  | Construct |
| 19 | UBE3A_HUMAN | Q05086 | UBE3A | HECT | 20210701; 19591933; 19664228; 15371341; 19204938; 18298802; 16482544; 20589759; 17131388; 19759827; 17947517; 19164530; 17108031; 16951183; 20559465 | 42 |  | Construct |
| 20 | UBR5_HUMAN | O95071 | UBR5 | HECT | 18073532; 21127351; 21118991; 16601676; 16554297 | 24 |  | Construct |
| 21 | WWP1_HUMAN | Q9H0M0 | WWP1 | HECT | 19561640; 19047365; 20157612; 20951678; 18806757; 19307600; 17050664; 20694673 | 17 |  | Construct |
| 22 | UBE3C_HUMAN | Q15386 | UBE3C | HECT | 21167755; 20008553 | 17 |  | Construct |
| 23 | HERC6_HUMAN | Q8IVU3 | HERC6 | HECT | 20133869 | 5 |  | Construct |
| 24 | HECD2_HUMAN | Q5U5R9 | HECTD2 | HECT | 20175895; 19214206 | 1 |  | Construct |
| 25 | UBE3B_HUMAN | Q7Z3V4 | UBE3B | HECT | 12689446 | 1 |  | Construct |
| 26 | HECD4_HUMAN | Q9Y4D8 | HECTD4 | HECT | 20175895 | 0 | --- | --- |
| 27 | HACE1_HUMAN | Q8IYU2 | HACE1 | HECT | 15254018; 20175895 | 0 | --- | --- |
| 28 | UBE3D_HUMAN | Q7Z6J8 | UBE2CBP | HECT | 15749827 | 0 | --- | --- |
| 29 | TRAF2_HUMAN | Q12933 | TRAF2 | RING | 17878343; 12591926; 20047764; 18671942; 19854138; 18997792; 16936264 | 125 |  | Construct |
| 30 | CNOT4_HUMAN | O95628 | CNOT4 | RING | 19346402 | 17 |  | Construct |
| 31 | LNX1_HUMAN | Q8TBB1 | LNX1 | RING | 17936276 | 28 |  | Construct |
| 32 | PELI1_HUMAN | Q96FA3 | PELI1 | RING | 16884718 | 3 |  | Construct |
| 33 | DTX2_HUMAN | Q86UW9 | DTX2 | RING | 12670957 | 11 |  | Construct |
| 34 | TRI33_HUMAN | Q9UPN9 | TRIM33 | RING | 17189380; 15820681 | 26 |  | Construct |
| 35 | AMFR_HUMAN | Q9UKV5 | AMFR | RING | 18037895; 19103148; 19164805; 17895372; 20458442; 20133640; 19828134; 16168377 | 18 |  | Construct |
| 36 | RN181_HUMAN | Q9P0P0 | RNF181 | RING | 18331836 | 6 |  | Construct |
| 37 | MARH8_HUMAN | Q5T0T0 | MARCH8 | RING | 12582153; 19703975; 16619033 | 1 |  | Construct |
| 38 | PJA2_HUMAN | O43164 | PJA2 | RING | 12036302 | 9 |  | Construct |
| 39 | NSE1_HUMAN | Q8WV22 | NSMCE1 | RING | 20864041 | 6 |  | Construct |
| 40 | FANCL_HUMAN | Q9NW38 | FANCL | RING | 19622404; 19405097; 19805513 | 5 |  | Construct |
| 41 | RBX1_HUMAN | P62877 | RBX1 | RING | 12565873; 18826954; 20427290; 19424503; 17132228; 18279656 | 73 |  | Construct |
| 42 | BIRC3_HUMAN | Q13489 | BIRC3 | RING | 19279678; 19854138; 18997792; 20097753; 18997792; 16235027 | 31 |  | Construct |
| 43 | R113B_HUMAN | Q8IZP6 | RNF113B | RING | 19690564 | 2 |  | Construct |
| 44 | RN149_HUMAN | Q8NC42 | RNF149 | RING | 22628551 | 5 |  | Construct |
| 45 | GOLI_HUMAN | Q86XS8 | RNF130 | RING | 16549277 | 1 |  | Construct |
| 46 | RBBP6_HUMAN | Q7Z6E9 | RBBP6 | RING | 18851979; 20210701 | 21 |  | Construct |
| 47 | RNF5_HUMAN | Q99942 | RNF5 | RING | 19625452; 21148293; 19269966; 20483786 | 14 |  | Construct |
| 48 | PCGF1_HUMAN | Q9BSM1 | PCGF1 | RING | 18650381 | 9 |  | Construct |
| 49 | RNF26_HUMAN | Q9BY78 | RNF26 | RING | 11352657 | 6 |  | Construct |
| 50 | TRI22_HUMAN | Q8IYM9 | TRIM22 | RING | 19218198; 18656448; 19218198 | 4 |  | Construct |
| 51 | R144A_HUMAN | P50876 | RNF144A | RING | --- | 4 |  | Construct |
| 52 | BRCA1_HUMAN | P38398 | BRCA1 | RING | 12431996; 19887647; 18388150; 19164445; 19261748; 17283126; 16818604 | 170 |  | Construct |
| 53 | RFWD2_HUMAN | Q8NHY2 | RFWD2 | RING | 19643728; 18815134; 17588513; 19176998; 19007436; 14739464; 19741714; 21403399 | 26 |  | Construct |
| 54 | MUL1_HUMAN | Q969V5 | MUL1 | RING | 19741096; 19525920; 19407830; 20103533 | 9 |  | Construct |
| 55 | SHPRH_HUMAN | Q149N8 | SHPRH | RING | 18316726 | 6 |  | Construct |
| 56 | I2BP1_HUMAN | Q8IU81 | IRF2BP1 | RING | 18671972 | 1 |  | Construct |
| 57 | MAT1_HUMAN | P51948 | MNAT1 | RING | 16935935 | 142 |  | Construct |
| 58 | RO52_HUMAN | P19474 | TRIM21 | RING | 19571111; 18641315; 18687060; 19489724; 16472766; 19201866; 19675099; 18022694 | 17 |  | Construct |
| 59 | RNF8_HUMAN | O76064 | RNF8 | RING | 20656690; 18948756; 20080757; 19797077 | 13 |  | Construct |
| 60 | RN138_HUMAN | Q8WVD3 | RNF138 | RING | 16714285 | 5 |  | Construct |
| 61 | PZRN3_HUMAN | Q9UPQ7 | PDZRN3 | RING | 17576800 | 2 |  | Construct |
| 62 | BMI1_HUMAN | P35226 | BMI1 | RING | 19956605 | 31 |  | Construct |
| 63 | MYLIP_HUMAN | Q8WY64 | MYLIP | RING | 20427281; 19520913; 21343340; 19783832 | 3 |  | Construct |
| 64 | RAD18_HUMAN | Q9NS91 | RAD18 | RING | 20675655; 21355096; 19635810; 19228710 | 15 |  | Construct |
| 65 | SYVN1_HUMAN | Q86TM6 | SYVN1 | RING | 19835843; 21149444; 17141218; 14593114; 16847254; 17582219; 18369366; 20606367 | 14 |  | Construct |
| 66 | NFX1_HUMAN | Q12986 | NFX1 | RING | 15367597; 11447293 | 14 |  | Construct |
| 67 | RN125_HUMAN | Q96EQ8 | RNF125 | RING | 17460044; 19380491; 19893624 | 12 |  | Construct |
| 68 | PIAS2_HUMAN | O75928 | PIAS2 | RING | 17855618; 16148010; 18218142 | 95 |  | Construct |
| 69 | BIRC2_HUMAN | Q13490 | BIRC2 | RING | 19592251; 11907583; 19584093; 19506082; 19258326; 19223549; 17220297; 16282325; 21113135; 19854138; 18997792; 18082613; 16235027 | 29 |  | Construct |
| 70 | BRE1A_HUMAN | Q5VTR2 | RNF20 | RING | 19037095 | 10 |  | Construct |
| 71 | CIP1_HUMAN | Q9NPC3 | CCNB1IP1 | RING | 17784788; 17297447 | 4 |  | Construct |
| 72 | RN123_HUMAN | Q5XPI4 | RNF123 | RING | 15531880 | 4 |  | Construct |
| 73 | TIF1B_HUMAN | Q13263 | TRIM28 | RING | 18082607; 19584288 | 48 |  | Construct |
| 74 | RN111_HUMAN | Q6ZNA4 | RNF111 | RING | 14657019; 18451154; 17341133 | 17 |  | Construct |
| 75 | UBR1_HUMAN | Q8IWV7 | UBR1 | RING | 20537150; 20148194; 11526102 | 13 |  | Construct |
| 76 | RNF12_HUMAN | Q9NVW2 | RLIM | RING | 19683498; 17437998; 19117995; 19164295 | 11 |  | Construct |
| 77 | TRIM5_HUMAN | Q9C035 | TRIM5 | RING | 18312418 | 10 |  | Construct |
| 78 | CUL9_HUMAN | Q8IWT3 | CUL9 | RING | 17367545 | 4 |  | Construct |
| 79 | RN146_HUMAN | Q9NTX7 | RNF146 | RING | 15813938; 18326623 | 3 |  | Construct |
| 80 | SH3R2_HUMAN | Q8TEC5 | SH3RF2 | RING | 19945436;19389623 | 3 |  | Construct |
| 81 | DZIP3_HUMAN | Q86Y13 | DZIP3 | RING | 18206970 | 18 |  | Construct |
| 82 | CHFR_HUMAN | Q96EP1 | CHFR | RING | 19690564; 11807090; 19321445; 20388495 | 15 |  | Construct |
| 83 | UHRF2_HUMAN | Q96PU4 | UHRF2 | RING | 19218238; 14741369; 18643997 | 14 |  | Construct |
| 84 | R144B_HUMAN | Q7Z419 | RNF144B | RING | 17367545; 20615966; 20300062; 20864535 | 9 |  | Construct |
| 85 | RNF13_HUMAN | O43567 | RNF13 | RING | 21078126; 21078127; 20230530 | 7 |  | Construct |
| 86 | DTX4_HUMAN | Q9Y2E6 | DTX4 | RING | 22388039 | 1 |  | Construct |
| 87 | CBL_HUMAN | P22681 | CBL | RING | 10531381; 14989173; 18198176; 19578043; 19419964; 19265199; 19201892; 19081591; 14531861; 12145291; 18544533; 18519587; 17620338; 17446348; 17449471; 17395426; 16740632; 21041311; 11964285; 12881521; 12727845; 12649282; 15277517; 19880507; 19880496; 19401194; 16407834; 12593796; 12147253; 10854852; 17094949; 20643813; 17255943; 11904433; 12193575; 12218189; 21447956; 18034775; 16004964 | 111 |  | Construct |
| 88 | RAG1_HUMAN | P15918 | RAG1 | RING | 19118899; 21256161 | 6 |  | Construct |
| 89 | NHLC1_HUMAN | Q6VVB1 | NHLRC1 | RING | 19529779; 19171932 | 5 |  | Construct |
| 90 | BRAP_HUMAN | Q7Z569 | BRAP | RING | 16757328; 19091743; 19152073 | 4 |  | Construct |
| 91 | RFFL_HUMAN | Q8WZ73 | RFFL | RING | 18450452; 15069192 | 3 |  | Construct |
| 92 | LTN1_HUMAN | O94822 | LTN1 | RING | 19196968 | 3 |  | Construct |
| 93 | RNF11_HUMAN | Q9Y3C5 | RNF11 | RING | 20676133; 19262463 | 58 |  | Construct |
| 94 | RN185_HUMAN | Q96GF1 | RNF185 | RING | 20009572 | 36 |  | Construct |
| 95 | SIAH2_HUMAN | O43255 | SIAH2 | RING | 19631635; 19546213; 19423641; 11786535; 15064394; 15221006; 9334332; 15466852; 12072443; 14654780; 14645235; 11483518; 10747903; 9637679; 16141343; 20691163; 17716627 | 35 |  | Construct |
| 96 | TOPRS_HUMAN | Q9NS56 | TOPORS | RING | 17803295; 20429939; 19473992; 15247280; 20188669 | 29 |  | Construct |
| 97 | ARI2_HUMAN | O95376 | ARIH2 | RING | 20226183; 19664228 | 29 |  | Construct |
| 98 | HLTF_HUMAN | Q14527 | HLTF | RING | 18316726 | 17 |  | Construct |
| 99 | PCGF2_HUMAN | P35227 | PCGF2 | RING | 18211895 | 15 |  | Construct |
| 100 | DTX3L_HUMAN | Q8TDB6 | DTX3L | RING | 16809771 | 12 |  | Construct |
| 101 | BRE1B_HUMAN | O75150 | RNF40 | RING | 17478428 | 8 |  | Construct |
| 102 | MARH9_HUMAN | Q86YJ5 | MARCH9 | RING | 17604280; 17174307 | 1 |  | Construct |
| 103 | TRI74_HUMAN | Q86UV6 | TRIM74 | RING | 18398435 | 1 |  | Construct |
| 104 | MARH5_HUMAN | Q9NX47 | MARCH5 | RING | 19741096; 20851218; 20103533 | 8 |  | Construct |
| 105 | RN216_HUMAN | Q9NWF9 | RNF216 | RING | 20414355 | 5 |  | Construct |
| 106 | LITAF_HUMAN | Q99732 | LITAF | RING | 15776429 | 5 |  | Construct |
| 107 | RN135_HUMAN | Q8IUD6 | RNF135 | RING | 19017631 | 3 |  | Construct |
| 108 | MKRN1_HUMAN | Q9UHC7 | MKRN1 | RING | 21172006; 19846531 | 2 |  | Construct |
| 109 | RN182_HUMAN | Q8N6D2 | RNF182 | RING | 18298843 | 1 |  | Construct |
| 110 | MARHA_HUMAN | Q8NA82 | MARCH10 | RING | 21937444 | 1 |  | Construct |
| 111 | TRAF6_HUMAN | Q9Y4K3 | TRAF6 | RING | 19713527; 19494296; 19201866; 17947236; 17562858; 19898473; 19365808; 19232518; 17346928; 20047764; 17609522; 18824541; 18976280 | 361 |  | Construct |
| 112 | PRKN2_HUMAN | O60260 | PARK2 | RING | 18344614; 20194754; 17553932; 19663908; 19642705; 19875440; 19363481; 19229105; 17360614; 15492001; 20164189; 19880420; 21292769; 21173115; 17512523; 11739749; 21378096; 19146857; 15963499; 17059562 | 68 |  | Construct |
| 113 | MDM4_HUMAN | O15151 | MDM4 | RING | 18567799; 12393902 | 22 |  | Construct |
| 114 | TRI23_HUMAN | P36406 | TRIM23 | RING | 15684077; 18398435; 20724660 | 16 |  | Construct |
| 115 | MKRN3_HUMAN | Q13064 | MKRN3 | RING | --- | 14 |  | Construct |
| 116 | TRI41_HUMAN | Q8WV44 | TRIM41 | RING | 18248090; 17893151 | 10 |  | Construct |
| 117 | MYCB2_HUMAN | O75592 | MYCBP2 | RING | 18753128 | 9 |  | Construct |
| 118 | TRIM8_HUMAN | Q9BZR9 | TRIM8 | RING | 18248090; 20516148 | 9 |  | Construct |
| 119 | RN167_HUMAN | Q9H6Y7 | RNF167 | RING | 16314844 | 8 |  | Construct |
| 120 | BFAR_HUMAN | Q9NZS9 | BFAR | RING | 18805781; 21068390 | 7 |  | Construct |
| 121 | PELI3_HUMAN | Q8N2H9 | PELI3 | RING | 16884718 | 5 |  | Construct |
| 122 | PEX10_HUMAN | O60683 | PEX10 | RING | 19687296; 18644345 | 4 |  | Construct |
| 123 | TRI56_HUMAN | Q9BRZ2 | TRIM56 | RING | 21074459; 21289118 | 1 |  | Construct |
| 124 | TRI65_HUMAN | Q6PJ69 | TRIM65 | RING | 19690564 | 1 |  | Construct |
| 125 | MDM2_HUMAN | Q00987 | MDM2 | RING | 17545634; 16866370; 18802403; 18981217; 19032150; 14642282; 19713960; 19703557; 19128510; 19683495; 18451149; 18665269; 18948082; 19372219; 19369353; 19363159; 18784257; 19448429; 19345326; 19176998; 19321440; 19247369; 19219073; 17377491; 11927554; 15975924; 15242646; 15456867; 14769800; 20592017; 16678796; 16170383; 17301054; 15577944; 21460856; 21093410; 20453884 | 133 |  | Construct |
| 126 | PIAS1_HUMAN | O75925 | PIAS1 | RING | 20711444; 18755518; 19557165; 18511503; 17218271; 17066076; 14701874; 14500712; 16144832; 15961505; 15337742; 15280358; 20209145; 19843541; 20127678; 16678795; 16563226; 16568089; 19782030; 17509614; 15582666; 17938210; 18218142; 17101784; 15572666; 21467194; 17440973; 14644436 | 114 |  | Construct |
| 127 | PML_HUMAN | P29590 | PML | RING | 20130140 | 63 |  | Construct |
| 128 | TRI27_HUMAN | P14373 | TRIM27 | RING | 20145714 | 36 |  | Construct |
| 129 | TRI39_HUMAN | Q9HCM9 | TRIM39 | RING | 18248090 | 15 |  | Construct |
| 130 | MIB2_HUMAN | Q96AX9 | MIB2 | RING | 15920166 | 6 |  | Construct |
| 131 | RN220_HUMAN | Q5VTB9 | RNF220 | RING | 20170641 | 5 |  | Construct |
| 132 | TRI11_HUMAN | Q96F44 | TRIM11 | RING | 18248090; 18628401; 16904669 | 2 |  | Construct |
| 133 | MSL2_HUMAN | Q9HCI7 | MSL2 | RING | 19651615 | 1 |  | Construct |
| 134 | RNF6_HUMAN | Q9Y252 | RNF6 | RING | 19345326; 12874135; 19802004 | 1 |  | Construct |
| 135 | HAKAI_HUMAN | Q75N03 | CBLL1 | RING | 21283129; 19893985 | 1 |  | Construct |
| 136 | SIAH1_HUMAN | Q8IUQ4 | SIAH1 | RING | 20144232; 19631635; 18065497; 15163637; 11752454; 11146551; 14506261; 19218244; 17047048; 12072443; 15284290; 20471960; 18276110; 18280659; 17188242; 21185211; 18536714 | 43 |  | Construct |
| 137 | RNF4_HUMAN | P78317 | RNF4 | RING | 19380586; 20212317; 20026589 | 18 |  | Construct |
| 138 | CBLB_HUMAN | Q13191 | CBLB | RING | 19546233; 15308098; 11526404; 19815501; 19007436; 12218189 | 15 |  | Construct |
| 139 | RN168_HUMAN | Q8IYW5 | RNF168 | RING | 19500350; 20080757 | 11 |  | Construct |
| 140 | MGRN1_HUMAN | O60291 | MGRN1 | RING | 19703557; 19524515 | 10 |  | Construct |
| 141 | PJA1_HUMAN | Q8NG27 | PJA1 | RING | 11959851; 12036302; 18786927 | 9 |  | Construct |
| 142 | PELI2_HUMAN | Q9HAT8 | PELI2 | RING | 16884718; 17997719 | 9 |  | Construct |
| 143 | MIB1_HUMAN | Q86YT6 | MIB1 | RING | 17324930 | 8 |  | Construct |
| 144 | RN126_HUMAN | Q9BV68 | RNF126 | RING | 18819927; 18511420 | 7 |  | Construct |
| 145 | SH3R1_HUMAN | Q7Z6J0 | SH3RF1 | RING | 19393081; 16084064; 17420289 | 7 |  | Construct |
| 146 | TRI31_HUMAN | Q9BZY9 | TRIM31 | RING | 18248090 | 7 |  | Construct |
| 147 | TRI43_HUMAN | Q96BQ3 | TRIM43 | RING | 18248090 | 6 |  | Construct |
| 148 | MARH3_HUMAN | Q86UD3 | MARCH3 | RING | 17604280 | 5 |  | Construct |
| 149 | TRIM3_HUMAN | O75382 | TRIM3 | RING | 18248090 | 4 |  | Construct |
| 150 | MARH7_HUMAN | Q9H992 | MARCH7 | RING | 20962578; 19342884; 19901269 | 3 |  | Construct |
| 151 | SH3R3_HUMAN | Q8TEJ3 | SH3RF3 | RING | 20696164 | 3 |  | Construct |
| 152 | TRI69_HUMAN | Q86WT6 | TRIM69 | RING | 23131556 | 3 |  | Construct |
| 153 | TRIM6_HUMAN | Q9C030 | TRIM6 | RING | 18248090 | 2 |  | Construct |
| 154 | RN213_HUMAN | Q63HN8 | RNF213 | RING | 21799892 | 1 |  | Construct |
| 155 | TRIM4_HUMAN | Q9C037 | TRIM4 | RING | 18248090 | 1 |  | Construct |
| 156 | XIAP_HUMAN | P98170 | XIAP | RING | 19531477; 19473982; 17613533; 17217622; 20932476; 17967870; 12121969; 18761086 | 52 |  | Construct |
| 157 | PIAS4_HUMAN | Q8N2W9 | PIAS4 | RING | 20429939; 19625650; 19450230; 18063693; 17456046; 15713642; 20228053; 16622421; 19615980; 18974227; 17298944; 21079245; 20661221; 20471636; 17696781; 17585876 | 45 |  | Construct |
| 158 | BARD1_HUMAN | Q99728 | BARD1 | RING | 19176389 | 41 |  | Construct |
| 159 | TRAF3_HUMAN | Q13114 | TRAF3 | RING | 15084608; 12944909 | 41 |  | Construct |
| 160 | RING2_HUMAN | Q99496 | RNF2 | RING | 19956605; 19164757; 21245042; 17088979 | 33 |  | Construct |
| 161 | TRI63_HUMAN | Q969Q1 | TRIM63 | RING | 19506036; 19498199; 19240029; 17786241; 19850579; 21356357; 18222470 | 29 |  | Construct |
| 162 | RING1_HUMAN | Q06587 | RING1 | RING | 18643987; 19956605 | 25 |  | Construct |
| 163 | TRI25_HUMAN | Q14258 | TRIM25 | RING | 16352599; 20818395; 17418098; 20406818 | 24 |  | Construct |
| 164 | RN169_HUMAN | Q8NCN4 | RNF169 | RING | 22733822;22492721;22742833 | 24 |  | Construct |
| 165 | LRSM1_HUMAN | Q6UWE0 | LRSAM1 | RING | 19703557 | 22 |  | Construct |
| 166 | TIF1A_HUMAN | O15164 | TRIM24 | RING | 19584248 | 21 |  | Construct |
| 167 | ZN363_HUMAN | Q96PM5 | RCHY1 | RING | 20210701; 20598683; 18344599; 20357911 | 21 |  | Construct |
| 168 | RNF41_HUMAN | Q9H4P4 | RNF41 | RING | 17384230; 14765125; 18927152; 20628057 | 21 |  | Construct |
| 169 | TRI37_HUMAN | O94972 | TRIM37 | RING | 16306379 | 18 |  | Construct |
| 170 | DTX1_HUMAN | Q86Y01 | DTX1 | RING | 17463329; 15684388; 16277698 | 16 |  | Construct |
| 171 | PIAS3_HUMAN | Q9Y6X2 | PIAS3 | RING | 17066076; 15961505; 20935639; 20637912; 18212042 | 16 |  | Construct |
| 172 | TRAF5_HUMAN | O00463 | TRAF5 | RING | 20161788; 19893571 | 15 |  | Construct |
| 173 | RBX2_HUMAN | Q9UBF6 | RNF7 | RING | 18258608; 20103673; 18258608; 19325126 | 14 |  | Construct |
| 174 | VPS18_HUMAN | Q9P253 | VPS18 | RING | 16996030; 18772139; 16203730 | 14 |  | Construct |
| 175 | RNF14_HUMAN | Q9UBS8 | RNF14 | RING | 17367545 | 14 |  | Construct |
| 176 | DTX3_HUMAN | Q8N9I9 | DTX3 | RING | 12670957 | 13 |  | Construct |
| 177 | HOIL1_HUMAN | Q9BYM8 | RBCK1 | RING | 21455180; 18711448; 16643902; 16275334 | 13 |  | Construct |
| 178 | MARH6_HUMAN | O60337 | MARCH6 | RING | 19103148; 19651899; 20357004 | 13 |  | Construct |
| 179 | TRAIP_HUMAN | Q9BWF2 | TRAIP | RING | 17544371; 21068752 | 13 |  | Construct |
| 180 | CBLC_HUMAN | Q9ULV8 | CBLC | RING | 18239087 | 12 |  | Construct |
| 181 | TRI18_HUMAN | O15344 | MID1 | RING | 18949047 | 12 |  | Construct |
| 182 | RNF43_HUMAN | Q68DV7 | RNF43 | RING | 18313049; 21108931 | 10 |  | Construct |
| 183 | UBR2_HUMAN | Q8IWV8 | UBR2 | RING | 20298436 | 10 |  | Construct |
| 184 | ZNRF1_HUMAN | Q8ND25 | ZNRF1 | RING | 19648646; 20107048 | 9 |  | Construct |
| 185 | VPS41_HUMAN | P49754 | VPS41 | RING | 19690564 | 9 |  | Construct |
| 186 | RNF37_HUMAN | O94941 | UBOX5 | RING | 17050664 | 9 |  | Construct |
| 187 | TRI32_HUMAN | Q13049 | TRIM32 | RING | 18632609; 19349376; 19269368; 19155210; 16816390; 15316618 | 8 |  | Construct |
| 188 | RN114_HUMAN | Q9Y508 | RNF114 | RING | 18364390 | 8 |  | Construct |
| 189 | RN115_HUMAN | Q9Y4L5 | RNF115 | RING | 17462600; 18819927; 21179390 | 8 |  | Construct |
| 190 | RN19A_HUMAN | Q9NV58 | RNF19A | RING | 19741096; 19224863; 16513638 | 8 |  | Construct |
| 191 | RFWD3_HUMAN | Q6PCD5 | RFWD3 | RING | 20173098 | 7 |  | Construct |
| 192 | RN103_HUMAN | O00237 | RNF103 | RING | 21455683; 19753093 | 7 |  | Construct |
| 193 | TRI17_HUMAN | Q9Y577 | TRIM17 | RING | 19358823; 20559321; 20352094 | 7 |  | Construct |
| 194 | TRIM2_HUMAN | Q9C040 | TRIM2 | RING | 18687884 | 7 |  | Construct |
| 195 | TRIM9_HUMAN | Q9C026 | TRIM9 | RING | 20085810; 18248090; 19702650 | 7 |  | Construct |
| 196 | TTC3_HUMAN | P53804 | TTC3 | RING | 20059946; 20059950; 20059946 | 7 |  | Construct |
| 197 | RNF25_HUMAN | Q96BH1 | RNF25 | RING | 18757723 | 7 |  | Construct |
| 198 | PEX2_HUMAN | P28328 | PEX2 | RING | 19687296 | 6 |  | Construct |
| 199 | RNF38_HUMAN | Q9H0F5 | RNF38 | RING | 12874135 | 6 |  | Construct |
| 200 | TRI26_HUMAN | Q12899 | TRIM26 | RING | 18248090 | 6 |  | Construct |
| 201 | UHRF1_HUMAN | Q96T88 | UHRF1 | RING | 14993289; 21268065; 21045206 | 6 |  | Construct |
| 202 | RN128_HUMAN | Q8TEB7 | RNF128 | RING | 19542455; 20493730 | 5 |  | Construct |
| 203 | ZNRF4_HUMAN | Q8WWF5 | ZNRF4 | RING | 21205830 | 5 |  | Construct |
| 204 | ZMIZ2_HUMAN | Q8NF64 | ZMIZ2 | RING | 18218095 | 5 |  | Construct |
| 205 | ARI1_HUMAN | Q9Y4X5 | ARIH1 | RING | 17289916; 20212144; 15963499 | 5 |  | Construct |
| 206 | R113A_HUMAN | O15541 | RNF113A | RING | 19690564 | 5 |  | Construct |
| 207 | RN150_HUMAN | Q9ULK6 | RNF150 | RING | 19690564 | 5 |  | Construct |
| 208 | TRAF7_HUMAN | Q6Q0C0 | TRAF7 | RING | 20948544 | 5 |  | Construct |
| 209 | RN139_HUMAN | Q8WU17 | RNF139 | RING | 19720873; 20068067 | 4 |  | Construct |
| 210 | TRI35_HUMAN | Q9UPQ4 | TRIM35 | RING | 18248090 | 4 |  | Construct |
| 211 | BIRC7_HUMAN | Q96CA5 | BIRC7 | RING | 16729033 | 3 |  | Construct |
| 212 | ZMIZ1_HUMAN | Q9ULJ6 | ZMIZ1 | RING | 18218095 | 3 |  | Construct |
| 213 | RN19B_HUMAN | Q6ZMZ0 | RNF19B | RING | 16709802 | 3 |  | Construct |
| 214 | OSTM1_HUMAN | Q86WC4 | OSTM1 | RING | 12826607 | 3 |  | Construct |
| 215 | RNF31_HUMAN | Q96EP0 | RNF31 | RING | 21455180; 19237537; 21292167; 20614026 | 2 |  | Construct |
| 216 | TRIM1_HUMAN | Q9UJV3 | MID2 | RING | 18248090 | 2 |  | Construct |
| 217 | PEX12_HUMAN | O00623 | PEX12 | RING | 19687296 | 2 |  | Construct |
| 218 | TRI13_HUMAN | O60858 | TRIM13 | RING | 18248090; 21333377; 20100910; 17314412 | 2 |  | Construct |
| 219 | TRI38_HUMAN | O00635 | TRIM38 | RING | 18248090 | 2 |  | Construct |
| 220 | RN133_HUMAN | Q8WVZ7 | RNF133 | RING | 18574499 | 2 |  | Construct |
| 221 | TRI46_HUMAN | Q7Z4K8 | TRIM46 | RING | 18248090 | 2 |  | Construct |
| 222 | ZSWM2_HUMAN | Q8NEG5 | ZSWIM2 | RING | 16522193 | 2 |  | Construct |
| 223 | RN186_HUMAN | Q9NXI6 | RNF186 | RING | 19690564 | 2 |  | Construct |
| 224 | TRI34_HUMAN | Q9BYJ4 | TRIM34 | RING | 19690564 | 2 |  | Construct |
| 225 | RN152_HUMAN | Q8N8N0 | RNF152 | RING | 21203937 | 1 |  | Construct |
| 226 | RNF34_HUMAN | Q969K3 | RNF34 | RING | 15069192 | 1 |  | Construct |
| 227 | TRI51_HUMAN | Q9BSJ1 | SPRYD5 | RING | 18248090 | 1 |  | Construct |
| 228 | TRI36_HUMAN | Q9NQ86 | TRIM36 | RING | 19232519; 19675128 | 1 |  | Construct |
| 229 | TRI59_HUMAN | Q8IWR1 | TRIM59 | RING | 17314412 | 1 |  | Construct |
| 230 | TRI73_HUMAN | Q86UV7 | TRIM73 | RING | 18398435 | 1 |  | Construct |
| 231 | RNFT1_HUMAN | Q5M7Z0 | RNFT1 | RING | 19690564 | 1 |  | Construct |
| 232 | UNKL_HUMAN | Q9H9P5 | UNKL | RING | 20148946 | 1 |  | Construct |
| 233 | ZN645_HUMAN | Q8N7E2 | ZNF645 | RING | 20657603 | 0 | --- | --- |
| 234 | ZNRF2_HUMAN | Q8NHG8 | ZNRF2 | RING | 19648646 | 0 | --- | --- |
| 235 | MARH1_HUMAN | Q8TCQ1 | MARCH1 | RING | 19666567 | 0 | --- | --- |
| 236 | MARHB_HUMAN | A6NNE9 | MARCH11 | RING | 17604280 | 0 | --- | --- |
| 237 | MARH2_HUMAN | Q9P0N8 | MARCH2 | RING | 17980554 | 0 | --- | --- |
| 238 | MARH4_HUMAN | Q9P2E8 | MARCH4 | RING | 17686993 | 0 | --- | --- |
| 239 | RC3H1_HUMAN | Q5TC82 | RC3H1 | RING | 18036806; 19221396 | 0 | --- | --- |
| 240 | RFPLA_HUMAN | A6NLU0 | RFPL4A | RING | 11850190; 17071595; 12525704 | 0 | --- | --- |
| 241 | RN121_HUMAN | Q9H920 | RNF121 | RING | 20357004 | 0 | --- | --- |
| 242 | RN122_HUMAN | Q9H9V4 | RNF122 | RING | 20553626 | 0 | --- | --- |
| 243 | RN170_HUMAN | Q96K19 | RNF170 | RING | 21115467 | 0 | --- | --- |
| 244 | RN180_HUMAN | Q86T96 | RNF180 | RING | 18363970; 18358233 | 0 | --- | --- |
| 245 | RN187_HUMAN | Q5TA31 | RNF187 | RING | 20852630 | 0 | --- | --- |
| 246 | RN217_HUMAN | Q8TC41 | RNF217 | RING | 20682791 | 0 | --- | --- |
| 247 | TRI15_HUMAN | Q9C019 | TRIM15 | RING | 18248090 | 0 | --- | --- |
| 248 | TRI40_HUMAN | Q6P9F5 | TRIM40 | RING | 18248090 | 0 | --- | --- |
| 249 | TRI45_HUMAN | Q9H8W5 | TRIM45 | RING | 18248090 | 0 | --- | --- |
| 250 | TRI47_HUMAN | Q96LD4 | TRIM47 | RING | 18248090 | 0 | --- | --- |
| 251 | TRI50_HUMAN | Q86XT4 | TRIM50 | RING | 18398435 | 0 | --- | --- |
| 252 | TRI54_HUMAN | Q9BYV2 | TRIM54 | RING | 17360532; 17786241 | 0 | --- | --- |
| 253 | TRI62_HUMAN | Q9BVG3 | TRIM62 | RING | 18248090 | 0 | --- | --- |
| 254 | TRI68_HUMAN | Q6AZZ1 | TRIM68 | RING | 18451177 | 0 | --- | --- |
| 255 | ZNRF3_HUMAN | Q9ULT6 | ZNRF3 | RING | 18511420 | 0 | --- | --- |
| 256 | NSE2_HUMAN | Q96MF7 | NSMCE2 | RING | 16055714; 19793919 | 0 | --- | --- |
| 257 | LIN41_HUMAN | Q2Q1W2 | TRIM71 | RING | 19898466 | 0 | --- | --- |
| 258 | NEU1B_HUMAN | A8MQ27 | NEURL1B | RING | 17003037 | 0 | --- | --- |
| 259 | RNF24_HUMAN | Q9Y225 | RNF24 | RING | 11513855 | 0 | --- | --- |
| 260 | MEX3C_HUMAN | Q5U5Q3 | MEX3C | RING | 22863774;23446422 | 0 | --- | --- |
| 261 | MKRN2_HUMAN | Q9H000 | MKRN2 | RING | --- | 0 | --- | --- |
| 262 | MKRN4_HUMAN | Q13434 | MKRN4P | RING | --- | 0 | --- | --- |
| 263 | NEUL1_HUMAN | O76050 | NEURL1 | RING | 20847082 | 0 | --- | --- |
| 264 | NEUL3_HUMAN | Q96EH8 | NEURL3 | RING | --- | 0 | --- | --- |
| 265 | TRIML_HUMAN | Q8N9V2 | TRIML1 | RING | --- | 0 | --- | --- |
| 266 | DDB1_HUMAN | Q16531 | DDB1 | Other | 19276361; 19337321; 21237244 | 102 |  | Construct |
| 267 | ARNT_HUMAN | P27540 | ARNT | Other | 17392787 | 30 |  | Construct |
| 268 | APC13_HUMAN | Q9BS18 | ANAPC13 | Other | 21107322; 16763193 | 9 |  | Construct |
| 269 | AMRA1_HUMAN | Q9C0C7 | AMBRA1 | Other | 20562859 | 8 |  | Construct |
| 270 | CIKS_HUMAN | O43734 | TRAF3IP2 | Other | 19825828 | 7 |  | Construct |
| 271 | ASB4_HUMAN | Q9Y574 | ASB4 | Other | 17636018 | 7 |  | Construct |
| 272 | ASB6_HUMAN | Q9NWX5 | ASB6 | Other | 16325183 | 5 |  | Construct |
| 273 | ASB8_HUMAN | Q9H765 | ASB8 | Other | 12559969 | 5 |  | Construct |
| 274 | CDCA3_HUMAN | Q99618 | CDCA3 | Other | 18032919; 12679038 | 4 |  | Construct |
| 275 | ASB1_HUMAN | Q9Y576 | ASB1 | Other | 16325183 | 4 |  | Construct |
| 276 | ASB15_HUMAN | Q8WXK1 | ASB15 | Other | 16424087 | 4 |  | Construct |
| 277 | KCD11_HUMAN | Q693B1 | KCTD11 | Other | 20081843; 21237243 | 2 |  | Construct |
| 278 | DCA17_HUMAN | Q5H9S7 | DCAF17 | Other | 17588513 | 2 |  | Construct |
| 279 | APC11_HUMAN | Q9NYG5 | ANAPC11 | Other | 19690564; 21107322; 16763193 | 77 |  | Construct |
| 280 | DDB2_HUMAN | Q92466 | DDB2 | Other | 19109893; 15882621 | 21 |  | Construct |
| 281 | KLH22_HUMAN | Q53GT1 | KLHL22 | Other | 19995937 | 1 |  | Construct |
| 282 | APC10_HUMAN | Q9UM13 | ANAPC10 | Other | 21107322; 16763193 | 61 |  | Construct |
| 283 | FBX3_HUMAN | Q9UK99 | FBXO3 | Other | 18809579 | 3 |  | Construct |
| 284 | APC5_HUMAN | Q9UJX4 | ANAPC5 | Other | 21107322; 16763193 | 67 |  | Construct |
| 285 | APC4_HUMAN | Q9UJX5 | ANAPC4 | Other | 21107322; 16763193 | 62 |  | Construct |
| 286 | AURKA_HUMAN | O14965 | AURKA | Other | 17060341 | 116 |  | Construct |
| 287 | DCA13_HUMAN | Q9NV06 | DCAF13 | Other | 17588513 | 19 |  | Construct |
| 288 | DCA11_HUMAN | Q8TEB1 | DCAF11 | Other | 16964240 | 3 |  | Construct |
| 289 | CUL4A_HUMAN | Q13619 | CUL4A | Other | 19276361 | 111 |  | Construct |
| 290 | FBXW5_HUMAN | Q969U6 | FBXW5 | Other | 21725316; 18381890; 17588513 | 8 |  | Construct |
| 291 | ASB12_HUMAN | Q8WXK4 | ASB12 | Other | 16325183 | 4 |  | Construct |
| 292 | WDR5_HUMAN | P61964 | WDR5 | Other | 17041588; 17588513 | 48 |  | Construct |
| 293 | CDC16_HUMAN | Q13042 | CDC16 | Other | 21107322; 16763193 | 87 |  | Construct |
| 294 | ASB2_HUMAN | Q96Q27 | ASB2 | Other | 16325183; 19376791; 21119685 | 6 |  | Construct |
| 295 | APC7_HUMAN | Q9UJX3 | ANAPC7 | Other | 21107322; 16763193 | 65 |  | Construct |
| 296 | AIRE_HUMAN | O43918 | AIRE | Other | 14734522; 15150263; 17456468 | 49 |  | Construct |
| 297 | LIS1_HUMAN | P43034 | PAFAH1B1 | Other | 17588513 | 124 |  | Construct |
| 298 | FXL15_HUMAN | Q9H469 | FBXL15 | Other | 21572392 | 5 |  | Construct |
| 299 | KLH41_HUMAN | O60662 | KBTBD10 | Other | 15983046 | 2 |  | Construct |
| 300 | KLHL9_HUMAN | Q9P2J3 | KLHL9 | Other | 17543862; 15772280 | 1 |  | Construct |
| 301 | ANC2_HUMAN | Q9UJX6 | ANAPC2 | Other | 21107322; 16763193 | 71 |  | Construct |
| 302 | CDC26_HUMAN | Q8NHZ8 | CDC26 | Other | 21107322; 16763193 | 26 |  | Construct |
| 303 | DCNL1_HUMAN | Q96GG9 | DCUN1D1 | Other | 19617556 | 10 |  | Construct |
| 304 | ASB9_HUMAN | Q96DX5 | ASB9 | Other | 17148442 | 7 |  | Construct |
| 305 | FBXL2_HUMAN | Q9UKC9 | FBXL2 | Other | 21343341 | 3 |  | Construct |
| 306 | CORO7_HUMAN | P57737 | CORO7 | Other | 21130766 | 2 |  | Construct |
| 307 | DCA10_HUMAN | Q5QP82 | DCAF10 | Other | 17588513 | 2 |  | Construct |
| 308 | FBX40_HUMAN | Q9UH90 | FBXO40 | Other | 22033112 | 1 |  | Construct |
| 309 | DCA12_HUMAN | Q5T6F0 | DCAF12 | Other | 17588513 | 1 |  | Construct |
| 310 | SMU1_HUMAN | Q2TAY7 | SMU1 | Other | 17588513 | 1 |  | Construct |
| 311 | KLH42_HUMAN | Q9P2K6 | KLHDC5 | Other | 19261606 | 3 |  | Construct |
| 312 | CIAO1_HUMAN | O76071 | CIAO1 | Other | 17588513 | 46 |  | Construct |
| 313 | CCNF_HUMAN | P41002 | CCNF | Other | 20596027 | 9 |  | Construct |
| 314 | DCAF5_HUMAN | Q96JK2 | DCAF5 | Other | 17588513 | 2 |  | Construct |
| 315 | FBX11_HUMAN | Q86XK2 | FBXO11 | Other | 19580641 | 17 |  | Construct |
| 316 | KLHL2_HUMAN | O95198 | KLHL2 | Other | 21549840 | 4 |  | Construct |
| 317 | SPSB4_HUMAN | Q96A44 | SPSB4 | Other | 21199876 | 3 |  | Construct |
| 318 | DCA16_HUMAN | Q9NXF7 | DCAF16 | Other | 17588513 | 2 |  | Construct |
| 319 | NACC1_HUMAN | Q96RE7 | NACC1 | Other | 17699672 | 1 |  | Construct |
| 320 | MAGA6_HUMAN | P43360 | MAGEA6 | Other | 17942928;20864041 | 42 |  | Construct |
| 321 | ERCC8_HUMAN | Q13216 | ERCC8 | Other | 18794354; 18936169 | 40 |  | Construct |
| 322 | TLE3_HUMAN | Q04726 | TLE3 | Other | 17041588; 17588513 | 13 |  | Construct |
| 323 | DCAF4_HUMAN | Q8WV16 | DCAF4 | Other | 17588513 | 2 |  | Construct |
| 324 | HXB4_HUMAN | P17483 | HOXB4 | Other | 21098278 | 2 |  | Construct |
| 325 | KLHL8_HUMAN | Q9P2G9 | KLHL8 | Other | 19158078 | 26 |  | Construct |
| 326 | KLH10_HUMAN | Q6JEL2 | KLHL10 | Other | 16162871 | 1 |  | Construct |
| 327 | FBX32_HUMAN | Q969P5 | FBXO32 | Other | 19117950; 15531760; 18354498; 19850579 | 3 |  | Construct |
| 328 | DCA15_HUMAN | Q66K64 | DCAF15 | Other | 17588513 | 2 |  | Construct |
| 329 | RHBT3_HUMAN | O94955 | RHOBTB3 | Other | 18835386 | 1 |  | Construct |
| 330 | ELOB_HUMAN | Q15370 | TCEB2 | Other | 17361105; 9606976 | 63 |  | Construct |
| 331 | TNAP3_HUMAN | P21580 | TNFAIP3 | Other | 19380636 | 33 |  | Construct |
| 332 | SPOP_HUMAN | O43791 | SPOP | Other | 19164706; 15897469; 20463034; 18414007 | 22 |  | Construct |
| 333 | TLE2_HUMAN | Q04725 | TLE2 | Other | 17041588; 17588513 | 12 |  | Construct |
| 334 | FBXL3_HUMAN | Q9UKT7 | FBXL3 | Other | 17463251; 20304803 | 6 |  | Construct |
| 335 | FBX18_HUMAN | Q8NFZ0 | FBXO18 | Other | 15117950 | 5 |  | Construct |
| 336 | SOCS4_HUMAN | Q8WXH5 | SOCS4 | Other | 17997974 | 5 |  | Construct |
| 337 | ASB7_HUMAN | Q9H672 | ASB7 | Other | 16325183 | 4 |  | Construct |
| 338 | M3K1_HUMAN | Q13233 | MAP3K1 | Other | 12049732; 17101801 | 133 |  | Construct |
| 339 | CUL4B_HUMAN | Q13620 | CUL4B | Other | 17954973; 21352845 | 96 |  | Construct |
| 340 | RBBP4_HUMAN | Q09028 | RBBP4 | Other | 17588513 | 68 |  | Construct |
| 341 | APC1_HUMAN | Q9H1A4 | ANAPC1 | Other | 21107322; 16763193 | 66 |  | Construct |
| 342 | SOCS7_HUMAN | O14512 | SOCS7 | Other | 12052866 | 25 |  | Construct |
| 343 | SOCS5_HUMAN | O75159 | SOCS5 | Other | 15695332 | 22 |  | Construct |
| 344 | A16L1_HUMAN | Q676U5 | ATG16L1 | Other | 17588513 | 17 |  | Construct |
| 345 | FEM1B_HUMAN | Q9UK73 | FEM1B | Other | 15601820 | 9 |  | Construct |
| 346 | SPSB1_HUMAN | Q96BD6 | SPSB1 | Other | 21199876; 11384984 | 8 |  | Construct |
| 347 | KDM2B_HUMAN | Q8NHM5 | KDM2B | Other | 22825849 | 7 |  | Construct |
| 348 | LRC41_HUMAN | Q15345 | LRRC41 | Other | 11384984 | 6 |  | Construct |
| 349 | LLR1_HUMAN | Q96L50 | LRR1 | Other | 21074711 | 5 |  | Construct |
| 350 | FXL12_HUMAN | Q9NXK8 | FBXL12 | Other | 18660753 | 4 |  | Construct |
| 351 | KLH17_HUMAN | Q6TDP4 | KLHL17 | Other | 17062563 | 1 |  | Construct |
| 352 | RCBT1_HUMAN | Q8NDN9 | RCBTB1 | Other | 19256485 | 1 |  | Construct |
| 353 | CUL2_HUMAN | Q13617 | CUL2 | Other | 9122164; 9447969; 12149480 | 90 |  | Construct |
| 354 | ELOC_HUMAN | Q15369 | TCEB1 | Other | 17361105; 9606976 | 76 |  | Construct |
| 355 | MALT1_HUMAN | Q9UDY8 | MALT1 | Other | 18287044 | 19 |  | Construct |
| 356 | RBBP5_HUMAN | Q15291 | RBBP5 | Other | 17588513 | 14 |  | Construct |
| 357 | FBX25_HUMAN | Q8TCJ0 | FBXO25 | Other | 16714087 | 6 |  | Construct |
| 358 | DCAF8_HUMAN | Q5TAQ9 | DCAF8 | Other | 17588513 | 6 |  | Construct |
| 359 | FBX7_HUMAN | Q9Y3I1 | FBXO7 | Other | 18495667; 16510124 | 4 |  | Construct |
| 360 | KLH21_HUMAN | Q9UJP4 | KLHL21 | Other | 19995937 | 1 |  | Construct |
| 361 | MYC_HUMAN | P01106 | MYC | Other | --- | 737 |  | Construct |
| 362 | CUL5_HUMAN | Q93034 | CUL5 | Other | 19933325; 19385048 | 123 |  | Construct |
| 363 | FBW1A_HUMAN | Q9Y297 | BTRC | Other | 18166147; 18378670; 18460583; 18500245; 10074433; 18650423; 18354483; 19004823; 19631635; 19557001; 19478868; 19297328; 15082796; 19276348; 19270156; 19244340; 17965458; 10437795; 19211746; 19196987; 17217622; 14525958; 14988407; 20068069; 19929170; 16303288; 21173164; 18575781; 19797085; 16219772; 21402774; 21068446; 17445772 | 107 |  | Construct |
| 364 | PRP19_HUMAN | Q9UMS4 | PRPF19 | Other | 15601865; 20595234 | 12 |  | Construct |
| 365 | FBX33_HUMAN | Q7Z6M2 | FBXO33 | Other | 16797541 | 10 |  | Construct |
| 366 | FBX2_HUMAN | Q9UK22 | FBXO2 | Other | 21135578; 20854419 | 7 |  | Construct |
| 367 | RMD5B_HUMAN | Q96G75 | RMND5B | Other | 19690564 | 5 |  | Construct |
| 368 | FBX17_HUMAN | Q96EF6 | FBXO17 | Other | 18203720 | 1 |  | Construct |
| 369 | BACD2_HUMAN | Q13829 | TNFAIP1 | Other | 19782033 | 1 |  | Construct |
| 370 | CBP_HUMAN | Q92793 | CREBBP | Other | 19805293 | 183 |  | Construct |
| 371 | FUS_HUMAN | P35637 | FUS | Other | 19946338 | 113 |  | Construct |
| 372 | CBX4_HUMAN | O00257 | CBX4 | Other | 20148194; 17439403; 12679040; 17018294; 19615980; 19029252; 20098713 | 57 |  | Construct |
| 373 | PDE4D_HUMAN | Q08499 | PDE4D | Other | 15260978; 15576036 | 19 |  | Construct |
| 374 | BACD1_HUMAN | Q8WZ19 | KCTD13 | Other | 19782033 | 6 |  | Construct |
| 375 | NLE1_HUMAN | Q9NVX2 | NLE1 | Other | 17588513 | 5 |  | Construct |
| 376 | RWDD3_HUMAN | Q9Y3V2 | RWDD3 | Other | 20026589 | 4 |  | Construct |
| 377 | CAPS2_HUMAN | Q86UW7 | CADPS2 | Other | 19690564 | 4 |  | Construct |
| 378 | DCAF6_HUMAN | Q58WW2 | DCAF6 | Other | 17588513 | 2 |  | Construct |
| 379 | FBXL6_HUMAN | Q8N531 | FBXL6 | Other | 19159283 | 1 |  | Construct |
| 380 | MED8_HUMAN | Q96G25 | MED8 | Other | 12149480 | 32 |  | Construct |
| 381 | KLH13_HUMAN | Q9P2N7 | KLHL13 | Other | 17543862; 15772280 | 10 |  | Construct |
| 382 | FBX4_HUMAN | Q9UKT5 | FBXO4 | Other | 20181953; 19683498; 19343786; 19221502; 15520277 | 8 |  | Construct |
| 383 | CUL7_HUMAN | Q14999 | CUL7 | Other | 17332328 | 7 |  | Construct |
| 384 | PRC1_HUMAN | O43663 | PRC1 | Other | 9885575;12082078;15297875;15625105;16431929;19468300;20691902 | 7 |  | Construct |
| 385 | ASB3_HUMAN | Q9Y575 | ASB3 | Other | 15899873 | 5 |  | Construct |
| 386 | RB40C_HUMAN | Q96S21 | RAB40C | Other | 15601820 | 4 |  | Construct |
| 387 | FBX31_HUMAN | Q5XUX0 | FBXO31 | Other | 19412162 | 3 |  | Construct |
| 388 | FBSP1_HUMAN | P0C2W1 | FBXO45 | Other | 19996097; 19581926 | 2 |  | Construct |
| 389 | FBX44_HUMAN | Q9H4M3 | FBXO44 | Other | 20057081; 20682791; 14701835 | 1 |  | Construct |
| 390 | EP300_HUMAN | Q09472 | EP300 | Other | 12690203 | 219 |  | Construct |
| 391 | CUL1_HUMAN | Q13616 | CUL1 | Other | 18644861 | 186 |  | Construct |
| 392 | FBXW7_HUMAN | Q969H0 | FBXW7 | Other | 18500245; 11585921; 20208556; 19126544; 17574025; 18765672; 14739463; 20935640; 19660140; 18787170; 19364825; 15520277; 20534483; 20388706; 16054087; 12354302; 21368833; 20622901; 21254166 | 34 |  | Construct |
| 393 | KCTD5_HUMAN | Q9NXV2 | KCTD5 | Other | 18573101 | 10 |  | Construct |
| 394 | FBXW8_HUMAN | Q8N3Y1 | FBXW8 | Other | 17998335; 14990695; 18539111; 18498745; 17205132; 17588513 | 6 |  | Construct |
| 395 | DTL_HUMAN | Q9NZJ0 | DTL | Other | 19595719; 20932471; 21035370; 18703516; 20086099; 19081066 | 6 |  | Construct |
| 396 | GAN_HUMAN | Q9H2C0 | GAN | Other | 15983046; 15071497; 16227972; 18680552 | 5 |  | Construct |
| 397 | FBXL5_HUMAN | Q9UKA1 | FBXL5 | Other | 19762596; 17532294 | 3 |  | Construct |
| 398 | FBXW2_HUMAN | Q9UKT8 | FBXW2 | Other | 15640526 | 3 |  | Construct |
| 399 | FBXL7_HUMAN | Q9UJT9 | FBXL7 | Other | 22306998 | 2 |  | Construct |
| 400 | GBLP_HUMAN | P63244 | GNB2L1 | Other | 17244529 | 90 |  | Construct |
| 401 | CUL3_HUMAN | Q13618 | CUL3 | Other | 15071497 | 88 |  | Construct |
| 402 | CDC27_HUMAN | P30260 | CDC27 | Other | 20552012; 21107322; 16763193 | 84 |  | Construct |
| 403 | FZR_HUMAN | Q9UM11 | FZR1 | Other | 19098431; 19477924; 16810178; 16675394; 11741538; 19336465; 19270695; 18662541; 17726374; 18573889; 17631504; 17376772; 16287863; 14701726; 15144564; 20530197; 21199005; 21186356; 20966048; 20424596; 17618083; 12023018; 21439932; 21270054; 21177849; 20802534; 20729194; 20006513; 20348135; 20064487; 19101468 | 80 |  | Construct |
| 404 | TLE1_HUMAN | Q04724 | TLE1 | Other | 17041588; 17588513 | 55 |  | Construct |
| 405 | IRAK1_HUMAN | P51617 | IRAK1 | Other | 11397809;12860405;14684752;15084582;15465816;15767370;17997719;20400509 | 45 |  | Construct |
| 406 | SKP2_HUMAN | Q13309 | SKP2 | Other | 16352731; 19828607; 19117950; 18056467; 19660140; 21237244; 18660753; 18665269; 10559858; 19451650; 19429855; 15520277; 17908926; 16286470; 14592976; 12840033; 16103164; 15113913; 19615363; 19935701; 16951159; 12769844; 18071316; 17786314 | 39 |  | Construct |
| 407 | FBW1B_HUMAN | Q9UKB1 | FBXW11 | Other | 17873516; 16775333; 21310048; 18782782 | 33 |  | Construct |
| 408 | RHBT2_HUMAN | Q9BYZ6 | RHOBTB2 | Other | 18374159; 18835386 | 28 |  | Construct |
| 409 | FBX6_HUMAN | Q9NRD1 | FBXO6 | Other | 18203720; 19515249 | 6 |  | Construct |
| 410 | CISH_HUMAN | Q9NSE2 | CISH | Other | 19622774 | 5 |  | Construct |
| 411 | RHES_HUMAN | Q96D21 | RASD2 | Other | 19498170 | 4 |  | Construct |
| 412 | FXL14_HUMAN | Q8N1E6 | FBXL14 | Other | 19955572 | 3 |  | Construct |
| 413 | PHIP_HUMAN | Q8WWQ0 | PHIP | Other | 17588513 | 3 |  | Construct |
| 414 | DCNL3_HUMAN | Q8IWE4 | DCUN1D3 | Other | 19617556 | 2 |  | Construct |
| 415 | NUP43_HUMAN | Q8NFH3 | NUP43 | Other | 17588513 | 100 |  | Construct |
| 416 | SOCS1_HUMAN | O15524 | SOCS1 | Other | 16616006; 12228220; 19339690; 17183367; 10747851; 15021916 | 47 |  | Construct |
| 417 | RICTR_HUMAN | Q6R327 | RICTOR | Other | 21204013; 20832730 | 35 |  | Construct |
| 418 | KEAP1_HUMAN | Q14145 | KEAP1 | Other | 17046835; 19818716; 20930034; 20865015 | 28 |  | Construct |
| 419 | TBL1R_HUMAN | Q9BZK7 | TBL1XR1 | Other | 20547759; 19759827 | 23 |  | Construct |
| 420 | UBAC1_HUMAN | Q9BSL1 | UBAC1 | Other | 15531880;15746103 | 14 |  | Construct |
| 421 | WDR59_HUMAN | Q6PJI9 | WDR59 | Other | 17588513 | 12 |  | Construct |
| 422 | KLH12_HUMAN | Q53G59 | KLHL12 | Other | 18303015; 19805045 | 8 |  | Construct |
| 423 | GRWD1_HUMAN | Q9BQ67 | GRWD1 | Other | 17588513 | 3 |  | Construct |
| 424 | KTNB1_HUMAN | Q9BVA0 | KATNB1 | Other | 17588513 | 2 |  | Construct |
| 425 | VHL_HUMAN | P40337 | VHL | Other | 20300531; 19228690; 12912922; 19695223; 19305426; 20026589; 11574546; 11739384; 12604794; 17350623; 15777842 | 191 |  | Construct |
| 426 | RBP2_HUMAN | P49792 | RANBP2 | Other | 20543581; 18492068; 20429939; 17101795; 18439914; 18946085; 20087442; 17264123 | 131 |  | Construct |
| 427 | CDC20_HUMAN | Q12834 | CDC20 | Other | 18662541; 19339280; 19167333; 17908926; 17015473; 20937767; 21439932; 11742988 | 124 |  | Construct |
| 428 | KAT2B_HUMAN | Q92831 | KAT2B | Other | 17293853; 19176998; 21374733 | 75 |  | Construct |
| 429 | CDC23_HUMAN | Q9UJX2 | CDC23 | Other | 21107322; 16763193 | 73 |  | Construct |
| 430 | SOCS3_HUMAN | O14543 | SOCS3 | Other | 16616006; 12228220 | 55 |  | Construct |
| 431 | HDAC4_HUMAN | P56524 | HDAC4 | Other | 18820298; 17218271; 15743823; 17218271; 19782030; 16166628; 19923268 | 47 |  | Construct |
| 432 | RBBP7_HUMAN | Q16576 | RBBP7 | Other | 17588513 | 47 |  | Construct |
| 433 | PWP1_HUMAN | Q13610 | PWP1 | Other | 17588513 | 45 |  | Construct |
| 434 | CHIP_HUMAN | Q9UNE7 | STUB1 | Other | 17525155; 17873020; 18381433; 18655187; 18313385; 19103148; 19741096; 18922468; 18955503; 19706771; 15466472; 19642705; 19536328; 19020010; 19483080; 19153604; 19465479; 19406989; 15538384; 17178836; 16740632; 16280320; 14612456; 15761032; 21358815; 19940151; 21124777; 20924358; 19940115; 19913553; 20588253; 17963781; 20724525; 20075607; 17324930; 16940184; 16207813; 11557750; 12297498; 15781469 | 44 |  | Construct |
| 435 | UB2E3_HUMAN | Q969T4 | UBE2E3 | Other | 10343118;20061386 | 40 |  | Construct |
| 436 | RHBT1_HUMAN | O94844 | RHOBTB1 | Other | 18835386 | 39 |  | Construct |
| 437 | TBL1X_HUMAN | O60907 | TBL1X | Other | 18803400; 19759827 | 38 |  | Construct |
| 438 | GBB2_HUMAN | P62879 | GNB2 | Other | 17588513 | 37 |  | Construct |
| 439 | SOCS2_HUMAN | O14508 | SOCS2 | Other | 17997974; 17363902 | 24 |  | Construct |
| 440 | EED_HUMAN | O75530 | EED | Other | 17041588; 17588513 | 22 |  | Construct |
| 441 | UFL1_HUMAN | O94874 | UFL1 | Other | 20018847; 20368332 | 21 |  | Construct |
| 442 | UCHL1_HUMAN | P09936 | UCHL1 | Other | 12408865; 19707515 | 21 |  | Construct |
| 443 | AHR_HUMAN | P35869 | AHR | Other | 19651607; 17392787; 21397018 | 21 |  | Construct |
| 444 | WDR12_HUMAN | Q9GZL7 | WDR12 | Other | 17588513 | 20 |  | Construct |
| 445 | SNR40_HUMAN | Q96DI7 | SNRNP40 | Other | 17588513 | 18 |  | Construct |
| 446 | WDR82_HUMAN | Q6UXN9 | WDR82 | Other | 17588513 | 17 |  | Construct |
| 447 | WDR61_HUMAN | Q9GZS3 | WDR61 | Other | 17588513 | 15 |  | Construct |
| 448 | UBE4B_HUMAN | O95155 | UBE4B | Other | 16484223; 21317885; 20696387 | 14 |  | Construct |
| 449 | RABX5_HUMAN | Q9UJ41 | RABGEF1 | Other | 18772883; 17341663 | 11 |  | Construct |
| 450 | SOCS6_HUMAN | O14544 | SOCS6 | Other | 12052866; 21030588 | 11 |  | Construct |
| 451 | DCAF7_HUMAN | P61962 | DCAF7 | Other | 17588513 | 11 |  | Construct |
| 452 | KLH20_HUMAN | Q9Y2M5 | KLHL20 | Other | 20389280; 21670212 | 10 |  | Construct |
| 453 | UBR7_HUMAN | Q8N806 | UBR7 | Other | --- | 9 |  | Construct |
| 454 | TP4AP_HUMAN | Q8TEL6 | TRPC4AP | Other | 20551172 | 8 |  | Construct |
| 455 | WSB1_HUMAN | Q9Y6I7 | WSB1 | Other | 15965468; 19651899; 18093972; 17588513 | 7 |  | Construct |
| 456 | E4F1_HUMAN | Q66K89 | E4F1 | Other | 17110336; 19805293 | 6 |  | Construct |
| 457 | SNUT1_HUMAN | O43290 | SART1 | Other | 18838541 | 6 |  | Construct |
| 458 | IRAK4_HUMAN | Q9NWZ3 | IRAK4 | Other | 11960013;12538665;15084582;17217339;17337443;17997719;20400509 | 6 |  | Construct |
| 459 | NIPA_HUMAN | Q86WB0 | ZC3HC1 | Other | 16009132 | 5 |  | Construct |
| 460 | WDR26_HUMAN | Q9H7D7 | WDR26 | Other | 17588513 | 5 |  | Construct |
| 461 | TMF1_HUMAN | P82094 | TMF1 | Other | 15467733 | 4 |  | Construct |
| 462 | VPRBP_HUMAN | Q9Y4B6 | VPRBP | Other | 19595719; 19287380; 17360488; 17620334; 20178741; 20870715 | 4 |  | Construct |
| 463 | UBR4_HUMAN | Q5T4S7 | UBR4 | Other | 18162545 | 3 |  | Construct |
| 464 | SPSB2_HUMAN | Q99619 | SPSB2 | Other | 20603330 | 3 |  | Construct |
| 465 | WSB2_HUMAN | Q9NYS7 | WSB2 | Other | 17001306 | 3 |  | Construct |
| 466 | ABTB1_HUMAN | Q969K4 | ABTB1 | Other | 18429817; 18459963 | 3 |  | Construct |
| 467 | WDR5B_HUMAN | Q86VZ2 | WDR5B | Other | 17588513 | 3 |  | Construct |
| 468 | UBE4A_HUMAN | Q14139 | UBE4A | Other | 18069675 | 2 |  | Construct |
| 469 | FBX27_HUMAN | Q8NI29 | FBXO27 | Other | 18203720 | 2 |  | Construct |
| 470 | WDTC1_HUMAN | Q8N5D0 | WDTC1 | Other | 17588513 | 2 |  | Construct |
| 471 | ZFP91_HUMAN | Q96JP5 | ZFP91 | Other | 20682767 | 1 |  | Construct |
| 472 | FBXL4_HUMAN | Q9UKA2 | FBXL4 | Other | 21757720 | 1 |  | Construct |
| 473 | WDR76_HUMAN | Q9H967 | WDR76 | Other | 17588513 | 1 |  | Construct |
| 474 | UBR3_HUMAN | Q6ZT12 | UBR3 | Other | --- | 1 |  | Construct |
| 475 | NOSIP_HUMAN | Q9Y314 | NOSIP | Other | 12746455 | 0 | --- | --- |
| 476 | PPIL2_HUMAN | Q13356 | PPIL2 | Other | 16978875 | 0 | --- | --- |
| 477 | KCMF1_HUMAN | Q9P0J7 | KCMF1 | Other | 15581609 | 0 | --- | --- |
| 478 | DCNL2_HUMAN | Q6PH85 | DCUN1D2 | Other | 19617556 | 0 | --- | --- |
| 479 | PDLI2_HUMAN | Q96JY6 | PDLIM2 | Other | 17468759; 20889505 | 0 | --- | --- |
| 480 | STC1_HUMAN | P52823 | STC1 | Other | 21042649 | 0 | --- | --- |
| 481 | CRBN_HUMAN | Q96SW2 | CRBN | Other | 17588513; 20223979; 21207098 | 0 | --- | --- |
| 482 | I2BPL_HUMAN | Q9H1B7 | IRF2BPL | Other | 19690564; 17334524 | 0 | --- | --- |
| 483 | FBX22_HUMAN | Q8NEZ5 | FBXO22 | Other | 21768309 | 0 | --- | --- |
| 484 | FBX8_HUMAN | Q9NRD0 | FBXO8 | Other | 18094045 | 0 | --- | --- |
| 485 | FBW10_HUMAN | Q5XX13 | FBXW10 | Other | 20498703 | 0 | --- | --- |
| 486 | FBX42_HUMAN | Q6P3S6 | FBXO42 | Other | 21127074; 19509332 | 0 | --- | --- |
| 487 | FXL19_HUMAN | Q6PCT2 | FBXL19 | Other | 22660580 | 0 | --- | --- |
| 488 | NEUL2_HUMAN | Q9BR09 | NEURL2 | Other | 14960280 | 0 | --- | --- |
| 489 | KLHL7_HUMAN | Q8IXQ5 | KLHL7 | Other | 19520207 | 0 | --- | --- |
| 490 | KBTBD_HUMAN | C9JR72 | KBTBD13 | Other | 22542517 | 0 | --- | --- |
| 491 | KCD21_HUMAN | Q4G0X4 | KCTD21 | Other | 21472142 | 0 | --- | --- |
| 492 | KCTD6_HUMAN | Q8NC69 | KCTD6 | Other | 21472142 | 0 | --- | --- |
| 493 | BCL6B_HUMAN | Q8N143 | BCL6B | Other | 22279058 | 0 | --- | --- |
| 494 | ZBT18_HUMAN | Q99592 | ZNF238 | Other | 21474562 | 0 | --- | --- |
| 495 | WDR53_HUMAN | Q7Z5U6 | WDR53 | Other | 17588513 | 0 | --- | --- |
| 496 | POC1B_HUMAN | Q8TC44 | POC1B | Other | 17588513 | 0 | --- | --- |
| 497 | BRWD1_HUMAN | Q9NSI6 | BRWD1 | Other | 17588513 | 0 | --- | --- |
| 498 | AREL1_HUMAN | O15033 | AREL1 | Other | 23479728 | 0 | --- | --- |
| 499 | TRIMM_HUMAN | Q8N7C3 | TRIML2 | Other | --- | 0 | --- | --- |