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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.
PDBID: 3R4NTitle: OPTIMIZATION OF POTENT, SELECTIVE, AND ORALLY BIOAVAILABLE
PYRROLODINOPYRIMIDINE-CONTAINING INHIBITORS OF HEAT SHOCK PROTEIN 90.
IDENTIFICATION OF DEVELOPMENT CANDIDATE 2-AMINO-4-{4-CHLORO-2-[2-(4-
FLUORO-1H-PYRAZOL-1-YL)ETHOXY]-6-METHYLPHENYL}-N-(2,2-
DIFLUOROPROPYL)-5,7-DIHYDRO-6H-PYRROLO[3,4-D]PYRIMIDINE-6-CARBOXAMIDE
Molecule: HEAT SHOCK PROTEIN HSP 90-ALPHA Chain: A, B Fragment: UNP RESIDUES 9-225 Organism: HOMO SAPIENS Method: X-RAY DIFFRACTION First author: K.S.GAJIWALA Resolution[Å]: 2.00 R-VALUE: 0.186 |
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