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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.
PDBID: 3RKZTitle: DISCOVERY OF A STABLE MACROCYCLIC O-AMINOBENZAMIDE HSP90 INHIBITOR
CAPABLE OF SIGNIFICANTLY DECREASING TUMOR VOLUME IN A MOUSE XENOGRAFT
MODEL.
Molecule: HEAT SHOCK PROTEIN HSP 90-ALPHA Chain: A Fragment: N-TERMINAL DOMAIN, UNP RESIDUES 10-236 Organism: HOMO SAPIENS Method: X-RAY DIFFRACTION First author: C.W.ZAPF Resolution[Å]: 1.57 R-VALUE: 0.165 |
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