Protein Name: Autophagy-related protein 16-1
|
UniprotKB/SwissProt ID: A16L1_HUMAN (Q676U5)
Gene Name: ATG16L1
Synonyms: APG16L
Organism: Homo sapiens (Human).
Function: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Preautophagosomal structure membrane; Peripheral membrane protein (By similarity). Note=Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5 (By similarity). Localizes also to di
| |
|
Graphical Visualization of Ubiquitination Sites:
|
| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
|
