UniprotKB/SwissProt ID: ARI1_HUMAN (Q9Y4X5)
Gene Name: ARIH1
Synonyms: ARI, MOP6, UBCH7BP
Organism: Homo sapiens (Human).
Function: E3 ubiquitin-protein ligase, which catalyzes polyubiquitination of target proteins together with ubiquitin- conjugating enzyme E2 UBE2L3. May play a role in protein translation by mediating polyubiquitination of EIF4E2, leading to its subsequent degradation. Acts as the ligase involved in ISGylation of EIF4E2.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Note=Mainly cytoplasmic.
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