UniprotKB/SwissProt ID: CDC26_HUMAN (Q8NHZ8)
Gene Name: CDC26
Synonyms: ANAPC12, C9orf17
Organism: Homo sapiens (Human).
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus (By similarity).
|
PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. ) |
