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Protein Name: Probable cytosolic iron-sulfur protein assembly protein CIAO1

UniprotKB/SwissProt ID: CIAO1_HUMAN (O76071)

Gene Name: CIAO1

Synonyms: WDR39

Organism: Homo sapiens (Human).

Function: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
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Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR001680
IPR011046
IPR015943


The ubiquitination sites of CIAO1_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
153GDSWIC K SVLSEG CCCEEE E EEEEEC 34.17%2189047

The interacting network mediated by proteins: CIAO1_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes