UniprotKB/SwissProt ID: CPSF6_HUMAN (Q16630)
Gene Name: CPSF6
Synonyms: CFIM68
Organism: Homo sapiens (Human).
Function: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles.
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