UniprotKB/SwissProt ID: FBXL7_HUMAN (Q9UJT9)
Gene Name: FBXL7
Synonyms: FBL6, FBL7, KIAA0840
Organism: Homo sapiens (Human).
Function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome (By similarity). Note=Localizes to the centrosome during spindle formation (By similarity).
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