Protein Name: F-box/LRR-repeat protein 12
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UniprotKB/SwissProt ID: FXL12_HUMAN (Q9NXK8)
Gene Name: FBXL12
Synonyms: FBL12
Organism: Homo sapiens (Human).
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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