Protein Name: G2/M phase-specific E3 ubiquitin-protein ligase
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UniprotKB/SwissProt ID: G2E3_HUMAN (Q7L622)
Gene Name: G2E3
Synonyms: KIAA1333
Organism: Homo sapiens (Human).
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage.
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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