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Protein Name: Probable E3 ubiquitin-protein ligase HERC3

UniprotKB/SwissProt ID: HERC3_HUMAN (Q15034)

Gene Name: HERC3

Synonyms: KIAA0032

Organism: Homo sapiens (Human).

Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR000408
IPR000569
IPR009091


The ubiquitination sites of HERC3_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
1821KKLLNV K PGLEDL HHHCCC C CCHHHH 32.09%2190698

The interacting network mediated by proteins: HERC3_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes