Protein Name: Probable E3 ubiquitin-protein ligase HERC4
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UniprotKB/SwissProt ID: HERC4_HUMAN (Q5GLZ8)
Gene Name: HERC4
Synonyms: KIAA1593
Organism: Homo sapiens (Human).
Function: Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Note=shows a punctate cytoplasmic distribution.
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Graphical Visualization of Ubiquitination Sites:
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Overview of Protein Ubiquitination Sites with Functional and Structural Information | |
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