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Protein Name: Transcription factor AP-1

UniprotKB/SwissProt ID: JUN_HUMAN (P05412)

Gene Name: JUN

Organism: Homo sapiens (Human).

Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.

PDB :
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Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR002112
IPR004827
IPR005643
IPR008917
IPR011616
IPR015558


The ubiquitination sites of JUN_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
150DPVGSL K PHLRAK HHHHHH C CCCCCC 31.89%2189047

The interacting network mediated by proteins: JUN_HUMAN


Disease:
Disease database Database Entry Disease information
KEGGH00020 Colorectal cancer
Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes