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Protein Name: Leucine-rich repeat-containing protein 41

UniprotKB/SwissProt ID: LRC41_HUMAN (Q15345)

Gene Name: LRRC41

Synonyms: MUF1

Organism: Homo sapiens (Human).

Function: Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR001611


The ubiquitination sites of LRC41_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
1199SSLHTL K FRHLLF HHHHHH H HHCCCC 41.32%21890473
2339AGGTDL K RELHPP CCCCCC C CCCCCH 46.79%21906983
3375SSTSSY K RAPASS HHHHCC C CCCCCC 43.99%21890473

The interacting network mediated by proteins: LRC41_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes