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Protein Name: E3 ubiquitin-protein ligase listerin

UniprotKB/SwissProt ID: LTN1_HUMAN (O94822)

Gene Name: LTN1

Synonyms: C21orf10, C21orf98, KIAA0714, RNF160, ZNF294

Organism: Homo sapiens (Human).

Function: E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information


The ubiquitination sites of LTN1_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
1638MLLGDE K QSIVQA   54.83%21890473
2651KPLEIA K LVQKNP   55.65%21890473
3717KWNSLL K IIEKAC   47.10%21890473
4737LVTPWL K GDILGE   51.15%21890473
5992FKEQDI K TLPSHL   52.91%21890473
61140LSKEEK K EFSAQC   68.24%21890473
71355TLTYIS K EQLLSH   39.66%2189047

The interacting network mediated by proteins: LTN1_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes