Protein Name: Melanoma-associated antigen 6
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UniprotKB/SwissProt ID: MAGA6_HUMAN (P43360)
Gene Name: MAGEA6
Synonyms: MAGE6
Organism: Homo sapiens (Human).
Function: Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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