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Protein Name: E3 ubiquitin-protein ligase MARCH11

UniprotKB/SwissProt ID: MARHB_HUMAN (A6NNE9)

Gene Name: MARCH11

Organism: Homo sapiens (Human).

Function: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic vesicle membrane; Multi-pass membrane protein (By similarity).

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information