UniprotKB/SwissProt ID: MDM4_HUMAN (O15151)
Gene Name: MDM4
Synonyms: MDMX
Organism: Homo sapiens (Human).
Function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.
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PDB :
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