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Protein Name: Myc proto-oncogene protein

UniprotKB/SwissProt ID: MYC_HUMAN (P01106)

Gene Name: MYC

Synonyms: BHLHE39

Organism: Homo sapiens (Human).

Function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleoplasm. Nucleus, nucleolus.

PDB :
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Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR001092
IPR002418
IPR003327
IPR011598
IPR012682


The ubiquitination sites of MYC_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
152SEDIWK K FELLPT CHHHHH H HHCCCC 29.13%21906983
2148AKLVSE K LASYQA HHHHHH H HCCCCC 41.67%20972266
3157SYQAAR K DSGSPN CCCCCC C CCCCCC 52.07%21906983
4323KDYPAA K RVKLDS CCCCCC C CCCCCC 60.89%21906983
5355DTEENV K RRTHNV CCHHHH H HHHHHH 47.98%21906983
6389ELENNE K APKVVI CCCCCC C CCHHHH 72.60%21906983
7412VQAEEQ K LISEED HHHHHH H HHHHHH 51.58%2190698

The interacting network mediated by proteins: MYC_HUMAN


Disease:
Disease database Database Entry Disease information
HPRD01818Burkitt lymphoma
Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes