UniprotKB/SwissProt ID: NACC1_HUMAN (Q96RE7)
Gene Name: NACC1
Synonyms: BTBD14B, NAC1
Organism: Homo sapiens (Human).
Function: Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Note=Distribution in the cytoplasm is dependent on phosphorylation (By similarity).
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PDB :
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