Protein Name: Neuralized-like protein 2
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UniprotKB/SwissProt ID: NEUL2_HUMAN (Q9BR09)
Gene Name: NEURL2
Synonyms: C20orf163
Organism: Homo sapiens (Human).
Function: Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity).
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Graphical Visualization of Ubiquitination Sites:
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Overview of Protein Ubiquitination Sites with Functional and Structural Information | |
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