UniprotKB/SwissProt ID: PDLI2_HUMAN (Q96JY6)
Gene Name: PDLIM2
Organism: Homo sapiens (Human).
Function: Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Note=May be partially nuclear. Isoform 1: Cytoplasm, cytoskeleton. Note=Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN). Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Nucleus.
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PDB :
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