UbiNet

Protein Name: Peroxisome biogenesis factor 2

UniprotKB/SwissProt ID: PEX2_HUMAN (P28328)

Gene Name: PEX2

Synonyms: PAF1, PMP3, PMP35, PXMP3, RNF72

Organism: Homo sapiens (Human).

Function: Somewhat implicated in the biogenesis of peroxisomes.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome membrane; Multi-pass membrane protein.

Graphical Visualization of Ubiquitination Sites:

Overview of Protein Ubiquitination Sites with Functional and Structural Information

InterPro ID	Domain
IPR001841
IPR006845
IPR013083

The ubiquitination sites of PEX2_HUMAN

No.	Position	Ubiquitinated Peptide	Secondary Structure	Solvent Accessibility	Substrate Motifs	PubMed ID
1	338	FAGTQL K ILRFLV		%		21890473
2	457	LRTSFW K SVLAGP		%		2189047

The interacting network mediated by proteins: PEX2_HUMAN

Disease:

Disease database	Database Entry	Disease information
KEGG	H00205	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NAL
OMIM	170993	PEROXISOME BIOGENESIS FACTOR 2; PEX2 ;;PEROXISOMAL MEMBRANE PROTEIN 3; PXMP3 PEROXISOMAL MEM
OMIM	614866	PEROXISOME BIOGENESIS DISORDER 5A (ZELLWEGER); PBD5A
OMIM	614867	PEROXISOME BIOGENESIS DISORDER 5B; PBD5B
HPRD	01367	Refsum disease, infantile form
HPRD	01367	Zellweger syndrome 3

Metabolic pathway:

Kegg map ID	Pathway
map03008	Ribosome biogenesis in eukaryotes

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