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Protein Name: PH-interacting protein

UniprotKB/SwissProt ID: PHIP_HUMAN (Q8WWQ0)

Gene Name: PHIP

Synonyms: WDR11

Organism: Homo sapiens (Human).

Function: Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti- apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus (By similarity).

PDB :
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Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information


The ubiquitination sites of PHIP_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
165TYQNLV K YYRHLA   39.47%21890473
2400FKRREW K SILLDM   23.90%21890473
31005REQELM K IVGIKY   47.03%21890473
41032LDPDTG K LTGGSF   44.99%21890473
51150CRSLIY K PLDGEW   31.91%21890473
61393LIFSNS K AYTPSK   50.06%21890473
71528STSSAA K TFITKA   43.62%21890473
81542ASAIPG K TILENS   27.34%21890473
91736LVPASV K VLRRSN   32.81%2189047

The interacting network mediated by proteins: PHIP_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes