Protein Name: E3 ubiquitin-protein ligase RNF135
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UniprotKB/SwissProt ID: RN135_HUMAN (Q8IUD6)
Gene Name: RNF135
Organism: Homo sapiens (Human).
Function: Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm.
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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