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Protein Name: E3 ubiquitin-protein ligase RNF187

UniprotKB/SwissProt ID: RN187_HUMAN (Q5TA31)

Gene Name: RNF187

Organism: Homo sapiens (Human).

Function: E3 ubiquitin-protein ligase that acts as a coactivator of JUN-mediated gene activation in response to growth factor signaling via the MAP3K1 pathway, independently from MAPK8.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Predominantly located in the cytoplasm. Shuttles between the cytoplasm and the nucleus.

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information


The ubiquitination sites of RN187_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
1161SAAAVW K GHVMDR   32.32%21906983
2223AVSELE K KHRNLG   67.51%2190698

The interacting network mediated by proteins: RN187_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes