Protein Name: E3 ubiquitin-protein ligase RNF19B
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UniprotKB/SwissProt ID: RN19B_HUMAN (Q6ZMZ0)
Gene Name: RNF19B
Synonyms: IBRDC3, NKLAM
Organism: Homo sapiens (Human).
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic granule membrane; Multi-pass membrane protein.
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Graphical Visualization of Ubiquitination Sites:
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Overview of Protein Ubiquitination Sites with Functional and Structural Information | |
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