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Protein Name: E3 ubiquitin-protein ligase RNF19B

UniprotKB/SwissProt ID: RN19B_HUMAN (Q6ZMZ0)

Gene Name: RNF19B

Synonyms: IBRDC3, NKLAM

Organism: Homo sapiens (Human).

Function: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic granule membrane; Multi-pass membrane protein.

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information