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Protein Name: E3 ubiquitin-protein ligase RNF34

UniprotKB/SwissProt ID: RNF34_HUMAN (Q969K3)

Gene Name: RNF34

Organism: Homo sapiens (Human).

Function: Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol 5-phosphate and phosphatidylinositol 3- phosphate.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus speckle. Endomembrane system; Peripheral membrane protein.

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR000306
IPR001841
IPR003034
IPR011011