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Protein Name: TNF receptor-associated factor 5

UniprotKB/SwissProt ID: TRAF5_HUMAN (O00463)

Gene Name: TRAF5

Synonyms: RNF84

Organism: Homo sapiens (Human).

Function: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (Probable). Cytoplasm, cytosol.

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR001293
IPR001841
IPR002083
IPR008974
IPR012227
IPR013083
IPR013322