UniprotKB/SwissProt ID: TRI18_HUMAN (O15344)
Gene Name: MID1
Synonyms: FXY, RNF59, TRIM18, XPRF
Organism: Homo sapiens (Human).
Function: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Microtubule-associated. It is associated with microtubules throughout the cell cycle, co- localizing with cytoplasmic fibers in interphase and with the mitotic spindle and midbodi
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