logo
   Home | Network Analysis | Data Statistics | Quick Search by Swiss-Prot ID or Keyword

Menu:


Protein Name: E3 ubiquitin-protein ligase TRIM39

UniprotKB/SwissProt ID: TRI39_HUMAN (Q9HCM9)

Gene Name: TRIM39

Synonyms: RNF23, TFP

Organism: Homo sapiens (Human).

Function: E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Mitochondrion. Note=Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when colocalized with MOAP1.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR000315
IPR001841
IPR001870
IPR003877
IPR003879
IPR006574
IPR013083


The ubiquitination sites of TRI39_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
192SMVEIA K QLQAVK HHHHHH H HHHCCC 58.14%2189047

The interacting network mediated by proteins: TRI39_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes