Protein Name: E3 ubiquitin-protein ligase TRIM56
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UniprotKB/SwissProt ID: TRI56_HUMAN (Q9BRZ2)
Gene Name: TRIM56
Synonyms: RNF109
Organism: Homo sapiens (Human).
Function: E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity).
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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