Protein Name: Ubiquitin-conjugating enzyme E2 E3
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UniprotKB/SwissProt ID: UB2E3_HUMAN (Q969T4)
Gene Name: UBE2E3
Synonyms: UBCE4, UBCH9
Organism: Homo sapiens (Human).
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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