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Protein Name: Ubiquitin-associated domain-containing protein 1

UniprotKB/SwissProt ID: UBAC1_HUMAN (Q9BSL1)

Gene Name: UBAC1

Synonyms: GBDR1, KPC2, UBADC1

Organism: Homo sapiens (Human).

Function: Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

PDB :
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Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information


The ubiquitination sites of UBAC1_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
17MFVQEE K IFAGKV   42.23%21890473
2111DVSAEE K KKQDQK   57.69%21906983
3121DQKAPD K EAILRA   48.24%21890473
4154FQTELR K ILVSLI   53.68%21890473
5178DAVELF K KANAML   64.70%20639865
6179AVELFK K ANAMLD   39.27%21906983
7330WLLGDR K PSPEEL   55.37%2190698

The interacting network mediated by proteins: UBAC1_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes