Protein Name: Ubiquitin-protein ligase E3C
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UniprotKB/SwissProt ID: UBE3C_HUMAN (Q15386)
Gene Name: UBE3C
Synonyms: KIAA0010, KIAA10
Organism: Homo sapiens (Human).
Function: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus (Potential).
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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