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Protein Name: Ubiquitin conjugation factor E4 A

UniprotKB/SwissProt ID: UBE4A_HUMAN (Q14139)

Gene Name: UBE4A

Synonyms: KIAA0126

Organism: Homo sapiens (Human).

Function: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
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Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR003613
IPR013083

The ubiquitination sites of UBE4A_HUMAN

No. Position Ubiquitinated Peptide Secondary Structure Solvent Accessibility Substrate Motifs PubMed ID
1104NSDPSL K SGNGIP CCCCCC C CCCCCC 61.73%21906983
2317VEYIQP K DPTNGQ HHCCCC C CCCCHH 61.02%21906983
3531LHDQMV K INQNLH HHHCCH H HHHHHH 30.51%21906983
4766TYRESI K DLADYA CCHHHH H HHHHHH 56.84%21890473
5774LADYAS K NLEAMN HHHHHH H HHHHCC 58.33%21890473
6810QYLSKI K IQQIEK HHHHHH H HHHHHH 37.89%2190698
The interacting network mediated by proteins: UBE4A_HUMAN

Metabolic pathway:
Kegg map ID Pathway
map03008Ribosome biogenesis in eukaryotes
 
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© UbiNet's Team: Van-Nui Nguyen, Kai-Yao Huang, Prof. Tzong-Yi Lee, and Prof. K. Robert Lai: Department of Computer Science and Engineering, Yuan Ze University.