UbiNet

Protein Name: Ubiquitin conjugation factor E4 B

UniprotKB/SwissProt ID: UBE4B_HUMAN (O95155)

Gene Name: UBE4B

Synonyms: HDNB1, KIAA0684, UFD2

Organism: Homo sapiens (Human).

Function: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity).

PDB :
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Graphical Visualization of Ubiquitination Sites:

Overview of Protein Ubiquitination Sites with Functional and Structural Information

InterPro ID	Domain
IPR003613
IPR013083

The ubiquitination sites of UBE4B_HUMAN

No.	Position	Ubiquitinated Peptide	Secondary Structure	Solvent Accessibility	Substrate Motifs	PubMed ID
1	610	DVKVVE K YFSGPA	CCEEEE C CCCCCC	39.73%		21890473
2	702	QLSTKI K LETVDP	HHCCCC E EEEECC	41.65%		21906983
3	794	RTVEDL K NNESQW	HHHHHH H HHHHHH	70.78%		21890473
4	801	NNESQW K DSPLAT	HHHHHH C CCHHHH	40.46%		21890473
5	951	VQPRTQ K FFEMIE	CCCCHH H HHHHHH	51.94%		21890473
6	964	NHPLST K LLVPSL	CCHHHH H HHHHHH	36.13%		21890473
7	989	TSEFYD K FTIRYH	CHHHHH H HCCCCC	32.78%		21890473
8	1056	EVQEEM K NKEQWD	HHHHHH H HHHHCC	69.05%		21906983
9	1058	QEEMKN K EQWDQL	HHHHHH H HHCCCC	45.85%		21906983
10	1106	LTKQVQ K PFLRPE	HHHHHH H HHCCCH	38.59%		21890473
11	1189	FEEVIS K MRKAGI	HHHHHH H HHHHCC	31.44%		21890473
12	1203	STIAIE K FKLLAE	CHHHHH H HHHHHH	41.51%		21890473
13	1217	VEEIVA K NARAEI	HHHHHH H HHHHHH	40.00%		2190698

The interacting network mediated by proteins: UBE4B_HUMAN

Metabolic pathway:

Kegg map ID	Pathway
map03008	Ribosome biogenesis in eukaryotes

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